Results 71 to 80 of about 1,030,130 (316)

Energy Harvesting by a Novel Substitution for Expansion Valves: Special Focus on City Gate Stations of High-Pressure Natural Gas Pipelines [PDF]

, 2020
Yahya Sheikhnejad, João Simões, Nélson Martins   +2 more
openalex   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Microbial membrane transport genes in maize rhizosphere under fertilization – a preliminary study

Scientific Reports
Microbial DNA fragments isolated from maize rhizosphere soil under different soil fertilization treatments were sequenced, and the analysed genes contained membrane transport genes for the uptake and utilization of various substrates, nutrients ranging ...
Matthew Chekwube Enebe, Olubukola Oluranti Babalola   +1 more
doaj   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Bio-control potentials of Vachellia nilotica-derived silver nanoparticle against multidrug-resistant Staphylococcus haemolyticus strains from raw milk

Discover Materials
The global rise in multidrug-resistant (MDR) microorganisms has led to an increased need for innovative and more effective antimicrobials. Green nanotechnology is a promising therapeutic.
Daniel Jesuwenu Ajose, Tesleem Olatunde Abolarinwa, Bukola Opeyemi Oluwarinde, Sheriff Aweda Balogun, Omolola Esther Fayemi, Adeyemi Oladapo Aremu, Collins Njie Ateba   +6 more
doaj   +1 more source

ARC-NLP at PAN 2023: Transition-Focused Natural Language Inference for Writing Style Detection [PDF]

, 2023
Izzet Emre Kucukkaya, Ümitcan Şahin, Çağrı Toraman   +2 more
openalex   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Resolving Topic-Focus Ambiguities in Natural Language [PDF]

, 2012
Natural language has features that are not found in logically perfect artificial languages. One such feature is redundancy, where two or more terms/expressions share exactly the same semantic and logical (but perhaps not pragmatic or rhetoric) properties.
openaire   +2 more sources

Adoption of CRISPR-Cas for crop production: present status and future prospects [PDF]

PeerJ
Background Global food systems in recent years have been impacted by some harsh environmental challenges and excessive anthropogenic activities. The increasing levels of both biotic and abiotic stressors have led to a decline in food production, safety ...
Akinlolu Olalekan Akanmu, Michael Dare Asemoloye, Mario Andrea Marchisio, Olubukola Oluranti Babalola   +3 more
doaj   +2 more sources

Cotargeting TREM2 and IL2 pathways triggers multipronged anticancer immunity

Molecular Oncology, EarlyView.
Von Locquenghien et al. report that MiTE‐144, a triggering receptor expressed on myeloid cells 2 (TREM2) blocking antibody fused to interleukin‐2 (IL2) variant with tumour microenvironment restricted activation, demonstrates superior anticancer efficiency in a preclinical setting.
Isaure Vanmeerbeek, Jenny Sprooten, Abhishek D. Garg   +2 more
wiley   +1 more source