Results 61 to 70 of about 9,712,563 (292)
Emerging global challenges, such as antimicrobial resistance, have shifted the focus of natural product discovery from well-characterized microbial producers to underexplored taxonomic groups.
Yang Liu +11 more
doaj +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Focus Ireland annual report 1999.
Focus Ireland believes that everyone has the right to a place they can call home and to live a life with dignity at an acceptable standard of living. Sadly, however, this is not always the case for many people in Ireland despite the sometimes seemingly
Focus Ireland
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Artificial molecular machines and motors—Design and control of nanoscale motion
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley +1 more source
Soybean (Glycine max L.) is a major legume crop of global agricultural significance, and its yield is heavily dependent on the rhizospheric microbes.
Ijeoma Emelda Osuji +2 more
doaj +1 more source
Focus on Renewable Natural Resources Fiscal 1986 Annual Report
The bulletin features the Department of Wildland Recreation Management and its focus on the expanding tourism industry in Idaho. Articles discuss the coexistence of tourism and natural resource industries, renovation and expansion of the Taylor Ranch ...
John C. Hendee; Leon F. Neuenschwander; Howard Loewenstein; Various Contributors
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Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Drought severely limits sunflower (Helianthus annuus L.) productivity, necessitating sustainable microbial strategies to enhance plant resilience. Endophytic bacteria modulate plant stress responses through diverse plant growth‐promoting (PGP) traits ...
Muritala Muhammed +2 more
doaj +1 more source
Memòria del Parc Natural dels Ports 2023 [PDF]
Gestió efectuada durant el 2023 al Parc Natural dels Ports, destacar les accions estratègiques i les fites més rellevants en cada un dels àmbits i línies de treball.[es] Gestión efectuada durante el 2023 en el Parque Natural de Els Ports, destaca las ...
Parc Natural dels Ports
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