Results 91 to 100 of about 580,652 (288)

Normal‐Appearing White Matter Injury Mediates Chronic Deep Venous Hypoxia and Disease Progression in Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore how cerebral hypoxia and Normal‐Appearing White Matter (NAWM) integrity affect MS lesion burden and clinical course. Methods Seventy‐nine MS patients, including 13 clinically isolated syndrome (CIS) patients and 66 relapsing–remitting multiple sclerosis (RRMS) patients, and 44 healthy controls (HCs) were recruited from ...
Xinli Wang   +8 more
wiley   +1 more source

Scaling Reinforcement Learning Paradigms for Motor Control

open access: yes, 2003
Reinforcement learning offers a general framework to explain rewardrelated learning in artificial and biological motor control. However, current reinforcement learning methods rarely scale to high dimensional movement systems and mainly operate in ...
Vijayakumar, S.; id_orcid   +2 more
core  

CSF Monoamine Metabolites and Cognitive Trajectory in Early Parkinson's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Imaging and postmortem studies indicate that abnormalities in monoaminergic neurotransmission contribute to cognitive impairment in Parkinson's disease (PD). However, it remains uncertain if cerebrospinal fluid (CSF) monoamine metabolites can serve as biomarkers of cognitive decline in early PD.
Jing‐Yu Shao   +7 more
wiley   +1 more source

Acropora tenuis energy acquisition along a natural turbidity gradient

open access: yesFrontiers in Marine Science
Predicted future increases in both local and global stressors are expected to lead to elevated turbidity levels and an expansion of the geographical range of turbid coral reefs.
Adi Zweifler   +7 more
doaj   +1 more source

Elevated Connectivity During Language Processing Is Associated With Cognitive Performance in SeLECTS

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Self‐Limited Epilepsy with Centrotemporal Spikes (SeLECTS) is associated with language impairments despite seizures originating in the motor cortex, suggesting aberrant cross‐network interactions. Here we tested whether functional connectivity in SeLECTS during language tasks predicts language performance.
Wendy Qi   +8 more
wiley   +1 more source

On 'spot' evolution under an adverse pressure gradient

open access: yes, 2001
The unsteady travelling 'spots' or spot-like disturbances are produced, in an otherwise planar boundary layer, by an initial impulse/blip, from wall forcing or from nearby external forcing. Theory and computations are described for the evolving spot-like
Timoshin, SN, Smith, FT
core  

Natural gradient algorithms for training deep neural networks

open access: yes
In this thesis, we reduce the computation cost of a particular class of learning algorithms for Deep Neural Networks (DNNs; human-brain inspired artificial intelligence models).
Puiu, Constantin Octavian
core   +1 more source

Evaluation of Digital Technologies for Home‐Based Assessment in People With Amyotrophic Lateral Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Digital technologies hold promise for transforming healthcare by enhancing personalized treatments and offer valuable opportunities to improve patient care. Here, we evaluated several novel, self‐administered, home‐based, digital endpoints for their association with corresponding conventional standard clinical measures (primary) in ...
Arne Mueller   +14 more
wiley   +1 more source

T1 Over Squared Proton Density Ratio to Characterize Multiple Sclerosis Lesions

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Differentiating remyelinated from demyelinated lesions in MS remains challenging without histological confirmation. This study introduces the T1‐to‐PD2 ratio (TPR) imaging approach and evaluates its ability to characterize MS lesions alongside other quantitative MRI (qMRI) metrics. Methods Thirty individuals with MS (mean age: 47.5 ± 
Sarah J. Wright   +10 more
wiley   +1 more source

Efficient quantum circuits based on the quantum natural gradient

open access: yesPhysical Review Research
Efficient preparation of arbitrary entangled quantum states is crucial for quantum computation. This is particularly important for noisy intermediate-scale quantum simulators relying on variational hybrid quantum-classical algorithms.
Ananda Roy   +2 more
doaj   +1 more source

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