Results 81 to 90 of about 1,580,667 (265)

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

FEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão, Diogo M. Engrácia, Graça Soveral, Filipa Mendes   +3 more
wiley   +1 more source

Observational Study of the Natural Growth History of Peripheral Small-Cell Lung Cancer on CT Imaging. [PDF]

Diagnostics (Basel), 2023
Jiang X, Liu MW, Zhang X, Dong JY, Miao L, Sun ZH, Dong SS, Zhang L, Yang L, Li M.   +9 more
europepmc   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Study on the Mechanism of Elastic Instability Caused by Natural Growth in Orthotropic Material. [PDF]

Materials (Basel), 2022
Wu D, He L.
europepmc   +1 more source

Yeast Gcn2 retains activity following humanization of its auto‐phosphorylation region

FEBS Open Bio, EarlyView.
Using Saccharomyces cerevisiae as a model to study Gcn2 activation and regulation is limited by the lack of antibodies detecting phosphorylated Gcn2. To overcome this, we engineered Gcn2‐HsC, a yeast Gcn2 variant recognizable by commercial anti‐human phospho‐GCN2 antibodies.
Reuben A. Anderson, Anja H. Schiemann, Evelyn Sattlegger   +2 more
wiley   +1 more source

The natural growth history of persistent pulmonary subsolid nodules: Radiology, genetics, and clinical management. [PDF]

Front Oncol, 2022
Zhang Z, Zhou L, Yang F, Li X.
europepmc   +1 more source

Features of medical care and medical-demographic indicators in the Arctic regions of the Republic of Sakha (Yakutia)

Якутский медицинский журнал
The article presents a network of medical and preventive institutions, data on medical and demographic indicators in the Arctic regions of the Republic of Sakha (Yakutia) for 2000-2018.
T. E. Burtseva, S. S. Sleptsova, N. M. Gogolev, L. N. Afanaseva, E. A. Borisova, A. V. Korosteleva, A. M. Makarova, M. P. Slobodchikova   +7 more
doaj   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source

Temporal expression study of miRNAs in the crown tissues of winter wheat grown under natural growth conditions. [PDF]

BMC Genomics, 2021
Wang M, Yang C, Wei K, Zhao M, Shen L, Ji J, Wang L, Zhang D, Guo J, Zheng Y, Yu J, Zhu M, Liu H, Li YF.   +13 more
europepmc   +1 more source