Results 41 to 50 of about 180,589 (298)

City of Beaverton natural hazards mitigation plan [PDF]

open access: yes, 2003
364 pp. Includes maps, charts and figures in single file. Published November, 2003. Captured June 1, 2006.The Mitigation Plan contains background on the purpose of the plan, the methodology used to develop the plan, a profile of Beaverton, chapters on ...
Oregon Natural Hazards Workgroup   +1 more
core  

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, Volume 20, Issue 6, Page 1591-1611, June 2026.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

Coseismic Rupture Model and Tectonic Implications of the January 7 2022, Menyuan Mw 6.6 Earthquake Constraints from InSAR Observations and Field Investigation

open access: yesRemote Sensing, 2022
A Mw 6.6 earthquake struck Menyuan, Qinghai, China, on 7 January 2022. To determine the rupture parameters of this event, the coseismic InSAR deformation fields were mapped and further employed to estimate the focal mechanism.
Yongsheng Li   +8 more
doaj   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

Multi-hazard fragility assessment of bridges: Methodology and case study application [PDF]

open access: yes, 2022
Reliability of road systems and their critical components exposed to multiple natural hazards is on the frontline of engineering research during the last three decades since potential damage of infrastructure is strongly related to important direct and ...
Tsinidis, G   +4 more
core  

Modelling intra-dependencies to assess road network resilience to natural hazards [PDF]

open access: yes, 2020
International audienceEstimating the resilience of a road network (one of the essential critical infrastructures in times of crisis) to natural hazards is crucial in achieving the goals of disaster risk reduction (DRR).
Abdallah, Chadi   +5 more
core   +1 more source

The potential use of nature-based solutions as natural hazard mitigation measure for linear infrastructure in the Nordic Countries

open access: yesGeoenvironmental Disasters
Background Reliable infrastructure is vital for Nordic societies, but they face escalating climate risks. Climate change is increasing magnitude and frequency of floods, storms, and landslides, making adaptive solutions crucial.
Vittoria Capobianco   +6 more
doaj   +1 more source

Coulomb stress changes associated with the M7.3 Maduo earthquake and implications for seismic hazards

open access: yesNatural Hazards Research, 2021
On May 21, 2021, the M7.3 Maduo earthquake occurred within the Bayan Har Block, one of the most seismically active regions in the Tibetan Plateau. This aroused attention to the seismic hazards in this block.
Yujiang Li   +6 more
doaj   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

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