Results 101 to 110 of about 878,200 (341)

The accumulation of myeloid‐derived suppressor cells participates in abdominal infection‐induced tumor progression through the PD‐L1/PD‐1 axis

open access: yesMolecular Oncology, EarlyView.
This study explores how sepsis affects GC progression by creating an immunosuppressive environment. Our findings reveal that sepsis promotes immune dysregulation, enhancing tumor growth and metastasis. Targeting the PD‐1/PD‐L1 pathway with monoclonal antibodies shows potential for restoring immune function and improving outcomes in cancer patients ...
Yiding Wang   +10 more
wiley   +1 more source

Recognizing early MRI signs (or their absence) is crucial in diagnosing metachromatic leukodystrophy

open access: yesAnnals of Clinical and Translational Neurology, Volume 9, Issue 12, Page 1999-2009, December 2022., 2022
Abstract Objectives Metachromatic leukodystrophy (MLD) has characteristic white matter (WM) changes on brain MRI, which often trigger biochemical and genetic confirmation of the diagnosis. In early or pre‐symptomatic disease stages, these typical MRI changes might be absent, hampering early diagnosis.
Daphne H. Schoenmakers   +7 more
wiley   +1 more source

Elachista dimicatella sensu auctt.—a complex of neglected species diversity (Lepidoptera, Elachistidae) from European mountain systems [PDF]

open access: yesZooKeys
Elachista dimicatella Rebel, 1903, has so far been considered a species in Europe with restricted distribution from Ukraine to western France. The species occurs on mountainous regions.
Lauri Kaila, Peter Huemer
doaj   +3 more sources

Ditch the Gold Standard: Re-evaluating Conversational Question Answering [PDF]

open access: yesarXiv, 2021
Conversational question answering aims to provide natural-language answers to users in information-seeking conversations. Existing conversational QA benchmarks compare models with pre-collected human-human conversations, using ground-truth answers provided in conversational history.
arxiv  

Preproject ‘Swiss Virtual Natural History Collection’

open access: yesDatabase, 2023
Abstract The initiative ‘Swiss Natural History Collection Network’ (SwissCollNet) aims to improve the accessibility of the Swiss natural history collections for research, education and the wider public. In the 2021–24 funding period, SwissCollNet is identifying, prioritizing and digitizing as many collections as possible and building an ...
Ana Petrus   +2 more
openaire   +2 more sources

Anthropologically introduced biases in natural history collections, with a case study on the invertebrate paleontology collections from the middle Cambrian Spence Shale Lagerstätte

open access: yes, 2020
Natural history collections are critical for modern scientific investigations, which are greatly expanding on the potential data applications of historic specimens.
A. Whitaker, J. Kimmig
semanticscholar   +1 more source

Addressing persistent challenges in digital image analysis of cancer tissue: resources developed from a hackathon

open access: yesMolecular Oncology, EarlyView.
Large multidimensional digital images of cancer tissue are becoming prolific, but many challenges exist to automatically extract relevant information from them using computational tools. We describe publicly available resources that have been developed jointly by expert and non‐expert computational biologists working together during a virtual hackathon
Sandhya Prabhakaran   +16 more
wiley   +1 more source

The anterior nucleus of the thalamus plays a role in the epileptic network

open access: yesAnnals of Clinical and Translational Neurology, Volume 9, Issue 12, Page 2010-2024, December 2022., 2022
Abstract Objectives We investigated both the metabolic differences and interictal/ictal discharges of the anterior nucleus of the thalamus (ANT) in patients with epilepsy to clarify the relationship between the ANT and the epileptic network. Methods Nineteen patients with drug‐resistant epilepsy who underwent stereoelectroencephalography were studied ...
Hao Yan   +9 more
wiley   +1 more source

Topic-Guided Self-Introduction Generation for Social Media Users [PDF]

open access: yesarXiv, 2023
Millions of users are active on social media. To allow users to better showcase themselves and network with others, we explore the auto-generation of social media self-introduction, a short sentence outlining a user's personal interests. While most prior work profiles users with tags (e.g., ages), we investigate sentence-level self-introductions to ...
arxiv  

Robust acute myeloid leukemia engraftment in humanized scaffolds using injectable biomaterials and intravenous xenotransplantation

open access: yesMolecular Oncology, EarlyView.
Patient‐derived xenografts (PDXs) can be improved by implantation of a humanized niche. We tested different biomaterials and approaches, and demonstrate that the combination of an injectable biomaterial for scaffold creation plus an intravenous route for acute myeloid leukemia (AML) xenotransplantation provide the most convenient and robust approach to
Daniel Busa   +13 more
wiley   +1 more source

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