Dendritic cells steering antigen and leukocyte traffic in lymph nodes
Dendritic cells are key players in the activation of T cells and their commitment to effector function. In this In a Nutshell Review, we will discuss how dendritic cells guide the trafficking of antigen and leukocytes in the lymph node, thus influencing T‐cell activation processes. Dendritic cells (DCs) play a central role in initiating and shaping the
Enrico Dotta+3 more
wiley +1 more source
Analyzing Web Archives Through Topic and Event Focused Sub-collections [PDF]
Web archives capture the history of the Web and are therefore an important source to study how societal developments have been reflected on the Web. However, the large size of Web archives and their temporal nature pose many challenges to researchers interested in working with these collections.
arxiv +1 more source
Sherd Assemblages from Sites in Bowie, Cass, Gregg, Lamar, and Red River Counties in East Texas Held by the Sam Noble Oklahoma Museum of Natural History [PDF]
The Sam Noble Oklahoma Museum of Natural History (SNOMNH) has in their collections several assemblages of ancestral Caddo ceramic vessel sherds from sites in East Texas.
Nelson, Bo, Perttula, Timothy K.
core +1 more source
Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley +1 more source
Ditch the Gold Standard: Re-evaluating Conversational Question Answering [PDF]
Conversational question answering aims to provide natural-language answers to users in information-seeking conversations. Existing conversational QA benchmarks compare models with pre-collected human-human conversations, using ground-truth answers provided in conversational history.
arxiv
Natural history collections are critical for modern scientific investigations, which are greatly expanding on the potential data applications of historic specimens.
A. Whitaker, J. Kimmig
semanticscholar +1 more source
Critic's Choice Essay: "Support Your Local Herbarium" [PDF]
Are herbaria becoming threatened and endangered? Are natural science collections going extinct? These questions are being posed increasingly by amateur and professional biologists as we witness the closure, dispersion, and scaling back of natural history
Elisens, Wayne J.
core +1 more source
Characterization of fungal carbonyl sulfide hydrolase belonging to clade D β‐carbonic anhydrase
Here, we performed a functional analysis of the fungal enzymes belonging to clade D of the β‐class carbonic anhydrase family (β‐D‐CA). The β‐D‐CAs in the basidiomycete Gloeophyllum trabeum and the ascomycete Trichoderma harzianum showed very low activity in the hydration of CO2 but exhibited high activity in the hydrolysis of carbonyl sulfide (COS ...
Ryuka Iizuka+6 more
wiley +1 more source
Elachista dimicatella sensu auctt.—a complex of neglected species diversity (Lepidoptera, Elachistidae) from European mountain systems [PDF]
Elachista dimicatella Rebel, 1903, has so far been considered a species in Europe with restricted distribution from Ukraine to western France. The species occurs on mountainous regions.
Lauri Kaila, Peter Huemer
doaj +3 more sources
First insights into herbivore–plant interaction of the spurge hawkmoth and Euphorbia cyparissias
The spurge hawkmoth Hyles euphorbiae (Lepidoptera, Sphingidae) is an insect herbivore feeding exclusively on spurges (Euphorbia). These are toxic due to their secondary metabolites including diterpene esters with numerous harmful biological activities ...
Stephanie Fiedler+7 more
doaj +1 more source