Screening for lung cancer: A systematic review of overdiagnosis and its implications
Molecular Oncology, EarlyView.Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz +12 more
wiley +1 more source
Coping with eccentricities of natural history collection data. A commentary on: ‘Comparing fruiting phenology across two historical datasets: Thoreau’s observations and herbarium specimens’ [PDF]
, 2021 Stephen A. Harris
openalex +1 more source
Documenting Natural History Collections in GBIF [PDF]
Biodiversity Information Science and Standards, 2019 The Global Biodiversity Information Facility (GBIF) was established by governments in 2001, largely through the initiative and leadership of the natural history collections community, following the 1999 recommendation by a working group under the Megascience Forum (predecessor of the Global Science Forum) of the Organization for Economic Cooperation ...
Robertson, Tim +3 more
openaire +2 more sources
Molecular Oncology, EarlyView.CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir +12 more
wiley +1 more source
Mobile objects: the space of shells in eighteenth-century France [PDF]
, 2006 The frequent distinction made between scientific and purely amateur collections misrepresents the specificity of the field of eighteenth-century natural history.
Dietz, Bettina
core +1 more source
Molecular Oncology, EarlyView.A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He +8 more
wiley +1 more source
Zoo Store 1 at the Natural History Museum: Meeting National Standards [PDF]
, 2007 The Natural History Museum (NHM), London is at the forefront of natural history science, and a major player in developing standards for the care of these collections in museums. Around ten years ago, there was a great deal of activity developing policies
Carnall, M
core
The “Real Academia das Sciencias de Lisboa” and the adventure of Pierre Auguste Broussonet, a pioneer of Brazil's Ichthyology and of the scientific relationships between Portugal and France. [PDF]
, 2014 Pierre Auguste Broussonet appears to be the first researcher engaged in the study of the fishes from the Portuguese collections on Natural History, and especially the Royal Museum of Ajuda collections, including the utmost important one collected in ...
Antunes, Miguel +2 more
core +1 more source
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
A catalogue of the collections of Mexican amber at the Natural History Museum, London and National Museums Scotland, Edinburgh, UK [PDF]
, 2016 A catalogue is here provided of the pieces of Mexican amber with inclusions in the collections of the Natural History Museum, London, and National Museums Scotland, Edinburgh, both in the United Kingdom.
Crighton, Bill +3 more
core +1 more source