Results 61 to 70 of about 4,381,528 (386)

Rigid motion revisited: rigid quasilocal frames

, 2008
We introduce the notion of a rigid quasilocal frame (RQF) as a geometrically natural way to define a "system" in general relativity. An RQF is defined as a two-parameter family of timelike worldlines comprising the worldtube boundary of the history of a ...
Bel Ll, Eriksen E, Griffiths D J, Landau L D, Llosa J, Llosa J Soler D, Misner C W, Nakahara M, Norton J, Paul L McGrath, Richard J Epp, Robert B Mann, Stachel J   +12 more
core   +1 more source

The scale of population structure in Arabidopsis thaliana [PDF]

, 2010
The population structure of an organism reflects its evolutionary history and influences its evolutionary trajectory. It constrains the combination of genetic diversity and reveals patterns of past gene flow.
A Rafalski, A Storfer, Alexander Platt, Alison E. Anastasio, Andrew Hudson, BF Voight, BS Weir, CD Bustamante, Detlef Weigel, Diane Byers, Eric B. Holub, ES Buckler, Fabrice Roux, FX Pico, G Guillot, G Guillot, J Marchini, JB Beck, JF Wilkins, JF Wilkins, John Novembre, Jon Ågren, Joy Bergelson, Justin O. Borevitz, Kathleen Donohue, LJ Heyer, LL Knowles, Luz Rivero, M Nordborg, Magnus Nordborg, Matthew Horton, Megan Dunning, N Warthmann, NH Barton, Ni Wayan Mulyati, Norman Warthmann, Oliver Bossdorf, Olivier Loudet, P Lewis, Randy Scholl, RM Kliman, S Atwell, S Wright, SL O'Kane, T Maruyama, T Mitchell-Olds, T Sasaki, Valérie Le Corre, Y Li, Yan Li, Yu S. Huang   +50 more
core   +7 more sources

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

Long‐term dynamics of a cladoceran community from an early stage of lake formation in Lake Fukami‐ike, Japan

Ecology and Evolution, 2021
An increase in nutrient levels due to eutrophication has considerable effects on lake ecosystems. Cladocerans are intermediate consumers in lake ecosystems; thus, they are influenced by both the bottom‐up and top‐down effects that occur as eutrophication
Yurie Otake, Hajime Ohtsuki, Jotaro Urabe, Shigeko Kimura, Kazuyoshi Yamada, Takehito Yoshida   +5 more
doaj   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

Connotation and qualities of the Buddhist culture of Grand Canal

HTS Teologiese Studies/Theological Studies
The Buddhist culture of the Grand Canal arises from the interaction and dynamic interplay between Grand Canal culture and Buddhist culture. This cultural phenomenon is not merely a simple superimposition of two elements; rather, it represents a unique ...
Bosen Qiu, Di Lang
doaj   +1 more source

At the Edge of Resilience: Making Sense of COVID-19 from the Perspective of Environmental History

Journal for the History of Environment and Society, 2020
Natural disasters nearly always catch societies by surprise, even though in hindsight historians invariably conclude that being caught off-guard in this way was in fact unfounded as both the existence of the natural hazard which caused the disaster, and ...
Tim Soens, Raf De Bont, Maïka De Keyzer
doaj   +1 more source

Data handling methods and target detection results for multibeam and sidescan data collected as part of the search for SwissAir Flight 111 [PDF]

, 1999
The crash of SwissAir Flight 111, off Nova Scotia in September 1998, triggered one of the largest seabed search surveys in Canadian history. The primary search tools used were sidescan sonars (both conventional and focussed types) and multibeam sonars ...
Bradford, Jim, Hughes Clarke, John E., Lamplugh, Mike, Mayer, Larry A., Parrott, R, Shaw, John   +5 more
core   +1 more source

2016 Patellofemoral pain consensus statement from the 4th International Patellofemoral Pain Research Retreat, Manchester. Part 1: Terminology, definitions, clinical examination, natural history, patellofemoral osteoarthritis and patient-reported outcome measures

British Journal of Sports Medicine, 2016
Patellofemoral pain (PFP) typically presents as diffuse anterior knee pain, usually with activities such as squatting, running, stair ascent and descent.
K. Crossley, J. Stefanik, J. Selfe, N. Collins, I. Davis, C. Powers, J. Mcconnell, B. Vicenzino, D. Bazett-Jones, J. Esculier, D. Morrissey, M. Callaghan   +11 more
semanticscholar   +1 more source

Strength through diversity: how cancers thrive when clones cooperate

Molecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken, Maartje Witsen, Emile E. Voest, Krijn K. Dijkstra   +3 more
wiley   +1 more source