Results 51 to 60 of about 3,617,486 (301)

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen   +14 more
wiley   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

open access: yesFEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon   +6 more
wiley   +1 more source

Connotation and qualities of the Buddhist culture of Grand Canal

open access: yesHTS Teologiese Studies/Theological Studies
The Buddhist culture of the Grand Canal arises from the interaction and dynamic interplay between Grand Canal culture and Buddhist culture. This cultural phenomenon is not merely a simple superimposition of two elements; rather, it represents a unique ...
Bosen Qiu, Di Lang
doaj   +1 more source

At the Edge of Resilience: Making Sense of COVID-19 from the Perspective of Environmental History

open access: yesJournal for the History of Environment and Society, 2020
Natural disasters nearly always catch societies by surprise, even though in hindsight historians invariably conclude that being caught off-guard in this way was in fact unfounded as both the existence of the natural hazard which caused the disaster, and ...
Tim Soens, Raf De Bont, Maïka De Keyzer
doaj   +1 more source

Long‐term dynamics of a cladoceran community from an early stage of lake formation in Lake Fukami‐ike, Japan

open access: yesEcology and Evolution, 2021
An increase in nutrient levels due to eutrophication has considerable effects on lake ecosystems. Cladocerans are intermediate consumers in lake ecosystems; thus, they are influenced by both the bottom‐up and top‐down effects that occur as eutrophication
Yurie Otake   +5 more
doaj   +1 more source

Aquinas’ De malo and the Ostensibly Problematic Status of Natural Evil as Privation [PDF]

open access: yes, 2018
Arguments concerning the nature of natural evil vary in their conclusions depending on the particular approach with which they commence inquiry; one of the most contested conclusions regards evil as privation, sourcing its justification primarily from ...
Pertierra, Iñaki Xavier Larrauri
core   +1 more source

HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein

open access: yesFEBS Open Bio, EarlyView.
Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley   +1 more source

Remarkable Stability of Uropodina (Acari: Mesostigmata) Communities in Artificial Microhabitats: A Case Study of Bird Nest Boxes in Bory Tucholskie National Park

open access: yesDiversity
The presence of nest boxes not only increases the reproductive success of many passerine birds in transformed forest habitats, but they also constitute important artificial microhabitats for many groups of invertebrates.
Marta Kulczak   +4 more
doaj   +1 more source

Dead Wood as an Element Enriching Biodiversity of Forest Ecosystems: A Case Study Based on Mites from the Suborder Uropodina (Acari: Parasitiformes)

open access: yesDiversity, 2021
The importance of dead wood in forest ecosystems for the existence of invertebrates has been widely discussed in the literature. The major aim of this study is to test the hypothesis that the presence of dead wood in forests considerably increases the ...
Jerzy Błoszyk   +4 more
doaj   +1 more source

Tableaux for Policy Synthesis for MDPs with PCTL* Constraints

open access: yes, 2017
Markov decision processes (MDPs) are the standard formalism for modelling sequential decision making in stochastic environments. Policy synthesis addresses the problem of how to control or limit the decisions an agent makes so that a given specification ...
A Kučera   +11 more
core   +1 more source

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