Results 61 to 70 of about 3,617,486 (301)
Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function
FEBS Open Bio, EarlyView.We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke +4 more
wiley +1 more source
DiversityThe state of research into acarofauna in Polish national parks is very uneven. One of the least examined areas in this regard is Bory Tucholskie National Park (BTNP), established in 1996.
Jerzy Błoszyk +4 more
doaj +1 more source
A catalogue of bird bones: an exercise in semantic web practice [PDF]
, 2010 The vast databases of natural history collections are increasingly being made accessible through the internet. The challenge is to place this data in a wider context that may reach beyond the interests of scholars only.
Brewington, Seth D. +3 more
core +1 more source
FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
Ecology and EvolutionPlant responses to environmental heterogeneity depend on life‐history traits, which could relate to phenotypical and genetic characteristics. To elucidate this relationship, we examined the variation in population genetics and functional traits of short‐
Khurelpurev Oyundelger +6 more
doaj +1 more source
FEBS Open Bio, EarlyView.Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley +1 more source
Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis
FEBS Open Bio, EarlyView.Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho +4 more
wiley +1 more source
FEBS Open Bio, EarlyView.Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source
DiversityThere are 23 national parks in Poland, and only a few of them have been studied thoroughly with regard to acarofauna so far. One of the least-examined areas in this regard is Bory Tucholskie National Park (BTNP), established in 1996.
Wojciech Niedbała +5 more
doaj +1 more source
History without time : Buffon's Natural History, as a non-mathematical physique
, 2010 International audienceWhile "natural history" is practically synonymous with the name of Buffon, the term itself has been otherwise overlooked by historians of science.
Hoquet, Thierry
core +3 more sources