Results 41 to 50 of about 641,261 (289)

Elemental and isotopic analysis of leaves predicts nitrogen-fixing phenotypes

open access: yesScientific Reports
Nitrogen (N)-fixing symbiosis is critical to terrestrial ecosystems, yet possession of this trait is known for few plant species. Broader presence of the symbiosis is often indirectly determined by phylogenetic relatedness to taxa investigated via ...
Joshua R. Doby   +6 more
doaj   +1 more source

Bivalvia biostratigraphy of Aksütlü region (Hekimhan, NW Malatya, Türkiye) and paleoclimatological interpretations

open access: yesBulletin of the Mineral Research and Exploration
In this study, Early Miocene bivalve fauna obtained from Hekimhan Aksütlü locality is presented. Abundant and well-preserved ostreid samples are interesting in the area where molluscs have notbeen studied before.
Müjde Gürsoy
doaj   +1 more source

Natural History of Patients with X-ray-negative Dyspepsia in General Practice [PDF]

open access: yesBMJ, 1972
When 102 patients with dyspepsia who had normal findings on barium-meal examination in 1964 were interviewed in 1970, 85 of them (76%) were symptomatically improved, and only three were later shown to have a peptic ulcer. This suggests that "x-ray-negative dyspepsia" has a good prognosis in a general practice setting.
D W, Gregory   +3 more
openaire   +2 more sources

General guide to the exhibition halls of the American Museum of Natural History;

open access: yes, 1911
Eleventh and 12th eds. have title: Guide to the present exhibition halls of the American Museum of Natural History (with cover title: General guide to the exhibition halls); 1939 ed.
American Museum of Natural History.
openaire   +3 more sources

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Natural History: the sense of wonder, creativity and progress in ecology

open access: yesScientia Marina, 2001
This essay addresses the question of blending natural history and ecological wisdom into the genuine creativity exemplified by Prof. Ramon Margalef. Many have observed that modern biology is a triumph of precision over accuracy, and that ecology has ...
Paul K. Dayton, Enric Sala
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Home - About - Disclaimer - Privacy