Haematologica, 2009 Dasatinib, a dual tyrosine kinase inhibitor, is known to modulate or suppress T-cell activation and proliferation. We report a series of 8 patients who developed chronic peripheral lymphocytosis, identified as natural killer cells or natural killer/T ...
Dong Hwan Kim +7 more
doaj +3 more sources
Nanomaterial assisted natural killer cell therapy [PDF]
Frontiers in ImmunologyThe rising incidence of cancer has heightened interest in immune cell therapy, particularly the role of natural killer (NK) cells, which are essential components of the immune system.
Xuan Yu +5 more
doaj +2 more sources
Skin TLR7 triggering promotes accumulation of respiratory dendritic cells and natural killer cells. [PDF]
, 2012 The TLR7 agonist imiquimod has been used successfully as adjuvant for skin treatment of virus-associated warts and basal cell carcinoma. The effects of skin TLR7 triggering on respiratory leukocyte populations are unknown.
Baal, Nelli +9 more
core +12 more sources
Reduced proportion and activity of natural killer cells in patients with Graves’ disease
European Journal of Inflammation, 2020 Natural killer cells not only play important roles in protecting against viral infection and cancer but also involved in the pathogenesis of Graves’ disease.
Qingqing Yang +6 more
doaj +1 more source
BMC Immunology, 2019 Background Natural killer cell responses to virally-infected or transformed cells depend on the integration of signals received through inhibitory and activating natural killer cell receptors.
Alexandra Tremblay-McLean +4 more
doaj +1 more source
Measurement of uterine natural killer cell percentage in the periimplantation endometrium from fertile women and women with recurrent reproductive failure: establishment of a reference range [PDF]
, 2017 Background Uterine natural killer cells are the major leukocytes present in the periimplantation endometrium. Previous studies have found controversial differences in uterine natural killer cell percentage in women with recurrent reproductive ...
Chen, Xiaoyan +6 more
core +1 more source
Reduced NK cell IFN-γ secretion and psychological stress are independently associated with herpes zoster. [PDF]
PLoS ONE, 2018 The pathogenesis of herpes zoster is closely linked to reduced varicella-zoster virus-specific cell-mediated immunity. However, little is known about the interplay between natural killer cells and psychological stress in the pathogenesis of herpes zoster.
Choon Kwan Kim +5 more
doaj +1 more source
Evasion of NK cell immune surveillance via the vimentin-mediated cytoskeleton remodeling
Frontiers in Immunology, 2022 Cancer immunotherapy uses the immune system to achieve therapeutic effects; however, its effect is still limited. Therefore, in addition to immune checkpoint-based treatment, the development of other strategies that can inhibit cancer cells from ...
Jei-Ming Peng +8 more
doaj +1 more source
Short communication: NKG2C+ NK cells contribute to increases in CD16+CD56- cells in HIV type 1+ individuals with high plasma viral load. [PDF]
, 2012 Chronic HIV-1 infection results in the expansion of both NKG2C+ and CD16+CD56- human natural killer cells. NKG2C+ cells proliferate in response to human cytomegalovirus (HCMV) and expansion of the dysfunctional CD56-CD16+ natural killer (NK) cells is ...
Bower, Mark +5 more
core +1 more source
Natural Killer T and Natural Killer Cell-Based Immunotherapy Strategies Targeting Cancer
Biomolecules, 2023 Both natural killer T (NKT) and natural killer (NK) cells are innate cytotoxic lymphoid cells that produce inflammatory cytokines and chemokines, and their role in the innate immune response to tumors and microorganisms has been investigated. Especially,
Tomonori Iyoda +4 more
doaj +1 more source