Results 41 to 50 of about 3,192,470 (291)

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Cotargeting TREM2 and IL2 pathways triggers multipronged anticancer immunity

Molecular Oncology, EarlyView.
Von Locquenghien et al. report that MiTE‐144, a triggering receptor expressed on myeloid cells 2 (TREM2) blocking antibody fused to interleukin‐2 (IL2) variant with tumour microenvironment restricted activation, demonstrates superior anticancer efficiency in a preclinical setting.
Isaure Vanmeerbeek, Jenny Sprooten, Abhishek D. Garg   +2 more
wiley   +1 more source

Natural language processing for under-resourced languages: Developing a Welsh natural language toolkit

Computer Speech & Language, 2022
Abstract Language technology is becoming increasingly important across a variety of application domains which have become common place in large, well-resourced languages. However, there is a danger that small, under-resourced languages are being increasingly pushed to the technological margins. Under-resourced languages face significant challenges in
Cunliffe, D, Vlachidis, A, Williams, D, Tudhope, D   +3 more
openaire   +2 more sources

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

Molecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann, Eduardo García‐Galea, Alice O'Farrell, Zak Kinsella, Maxime Meylan, Florent Petitprez, Ingrid Arijs, Tom Venken, Hari Ps, Adrian Lärkeryd, Ian Miller, Janick Selves, Nadja Meindl‐Beinker, Fiorella Ruiz‐Pace, Elena Élez, Raquel Comas‐Navarro, Frank Lincoln, Dirk Fey, Gift Nyamundanda, Aoife Nolan, Joern Lewin, Raquel Perez‐Lopez, Jonathan Briody, Kathleen Bennett, Walter Kolch, David Matallanas, Alexander Kel, Enrique Arenas, Joaquín Arribas, Bart Ghesquière, Josep Tabernero, Julie Meilleroux, Deborah McNamara, Ray McDermott, Marvin Lim, Mary O'Reilly, Brian Bird, Lisa Stack, Lucia Moloney, Patrick Morris, Keith Egan, Maciej Milewski, Lars Scheuer, Joachim Behringer, Georg Bolz, Ramon Salazar, Cristina Santos, Andrea Ruiz, Orla Casey, Verena Murphy, Matthias Ebert, Livio Trusolino, Diether Lambrechts, Anguraj Sadanandam, Catherine Sautès‐Fridman, Jochen Prehn, Paolo Nuciforo, Jacques Fieschi, Florence Monville, Darran O'Connor, Wolf Fridman, Annette Byrne   +61 more
wiley   +1 more source

Measurement of event data from text

Frontiers in Political Science
We examine measurement concerns about computer-aided political event data in the state-of-the-art after 2015. The focus is on how to compare and quantify the mathematical and/or conceptual distance between what a machine codes/classifies from information
Patrick T. Brandt, Marcus Sianan
doaj   +1 more source

De re attitude reports about disjunctive attitudes

Слово.ру: балтийский акцент, 2022
This paper discusses the semantics of so-called de re propositional attitudes. According to the standard Kaplanian analysis, the semantics of such dicta contains existential quantifica­tion over functions that map the attitude holder and the object of ...
Ekaterina V. Vostrikova, Petr S. Kusliy
doaj   +1 more source

Putting Natural in Natural Language Processing

Findings of the Association for Computational Linguistics: ACL 2023, 2023
Human language is firstly spoken and only secondarily written. Text, however, is a very convenient and efficient representation of language, and modern civilization has made it ubiquitous. Thus the field of NLP has overwhelmingly focused on processing written rather than spoken language.
openaire   +2 more sources

Natural language concept analysis [PDF]

Proceedings of the Joint Conferences on New Methods in Language Processing and Computational Natural Language Learning - NeMLaP3/CoNLL '98, 1998
Can we do text analysis without phrase structure? We think the answer could be positive. In this paper we outline the basics of an underlying theory which yields hierarchical structure as the result of more abstract principles relating to the combinatorial properties of linguistic units.
Kamphuis, V., Sarbo, J.J.
openaire   +2 more sources

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

FEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies, Garth L. Maker, Ian F. Musgrave, Samantha Lodge   +3 more
wiley   +1 more source

Program Synthesis using Natural Language [PDF]

, 2015
Interacting with computers is a ubiquitous activity for millions of people. Repetitive or specialized tasks often require creation of small, often one-off, programs. End-users struggle with learning and using the myriad of domain-specific languages (DSLs)
Aditya Desai, Amey Karkare, Mark Marron, Msr Redmond, Msr Redmond, Nidhi Jain, Roy, Sailesh R Subhajit, Sumit Gulwani, Vineet Hingorani   +9 more
core   +1 more source