Results 41 to 50 of about 8,038,777 (287)
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Validity of the laws of Non-contradiction and Excluded middle; Logical or Psychological (Review of misunderstandings and misinterpretations, self-made accusations and types of fallacies in a criticism) [PDF]
حکمت معاصرIn Classical Logic, the law of non-contradiction and the law of excluded middle are considered theorems and have proof. Recently, Morteza Hajihosseini has written a book titled Two Non-Classical Logic Systems, A New Outlook on Elements of Logic (2017 ...
Morteza Hajihosseini +1 more
doaj +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
NATURAL LANGUAGE UNDERSTANDING
AI Magazine, 1980 This is an excerpt from the Handbook of Artificial Intelligence, a compendium of hundreds of articles about AI ideas, techniques, and programs being prepared at Stanford University by AI researchers and students from across the country. In addition to articles describing the specifics of various AI programming methods, the Handbook contains dozens of ...
openaire +3 more sources
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Notre Dame Journal of Formal Logic, 1991 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire +4 more sources
Neuroeconomics, Naturalism, and Language [PDF]
SSRN Electronic Journal, 2007 Neuroeconomics stays in the center of the ongoing naturalistic turn in economics. It portrays the individual as a complex system of decision making mechanisms and modules. This results into a conceptual tension with the standard economic notion of the unity of the actor that is a systemic property of economic coordination.
openaire +2 more sources
Unraveling the epigenetic code in cancer cell–tumor microenvironment crosstalk
Molecular Oncology, EarlyView.Epigenetic regulation is a key driver of cancer development and progression. Diverse epigenetic alterations in cancer cells and components of the tumor microenvironment (TME) orchestrate their communication through multiple mechanisms. We discuss how the epigenetic code coordinates bidirectional cancer cell–TME crosstalk to promote cancer progression ...
Ji Hoon Park, Mi‐Young Kim
wiley +1 more source
Measurement of event data from text
Frontiers in Political ScienceWe examine measurement concerns about computer-aided political event data in the state-of-the-art after 2015. The focus is on how to compare and quantify the mathematical and/or conceptual distance between what a machine codes/classifies from information
Patrick T. Brandt, Marcus Sianan
doaj +1 more source
Computing with words for solving the fuzzy shortest path problem [PDF]
تصمیم گیری و تحقیق در عملیاتPurpose: The purpose of this paper is to address decision-making challenges in shortest path problems where arc lengths are expressed using natural language rather than precise numerical values and to develop an enhanced A* algorithm for computing the ...
Jayanta Pratihar +4 more
doaj +1 more source