Results 81 to 90 of about 2,656,316 (308)

Viral population estimation using pyrosequencing [PDF]

, 2008
The diversity of virus populations within single infected hosts presents a major difficulty for the natural immune response as well as for vaccine design and antiviral drug therapy.
A Dempster, A Rambaut, AMN Tsibris, B Gaschen, Baback Gharizadeh, C Wang, Chunlin Wang, D O'Meara, DC Douek, E Domingo, E Halperin, EH Simpson, ES Lander, Glenn Tesler, GS Gottlieb, GW Tyson, H Fakhrai-Rad, I Malet, IM Rouzine, J Kececioglu, JE Hopcroft, JF Simons, K Chen, KJ Metzner, L Bacheler, L Doukhan, L Excoffier, Lior Pachter, LR Ford, M Breitbart, M Eigen, M Margulies, M Stephens, MA Nowak, MJ Gonzales, ML Collins, ML Sogin, Mostafa Ronaghi, MT Tammi, N Beerenwinkel, Nicholas Eriksson, Niko Beerenwinkel, P Jenkins, PA Pevzner, R Schmid, R Shankarappa, Robert W. Shafer, RP Dilworth, S Huse, S-Y Rhee, S-Y Rhee, Soo-Yon Rhee, VA Johnson, Yumi Mitsuya   +53 more
core   +7 more sources

Strength through diversity: how cancers thrive when clones cooperate

Molecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken, Maartje Witsen, Emile E. Voest, Krijn K. Dijkstra   +3 more
wiley   +1 more source

COMPARING TWO TRANSECT METHODS FOR THE DETECTION OF RED-BACKED SALAMANDERS [PDF]

, 2016
Typical monitoring methods for terrestrial salamanders are subject to extensive variation, driven by the environmental conditions in effect during sampling.
Killian, Michael D., McGhee, Jay D.
core   +2 more sources

Japanese population dose from natural radiation

Journal of Radiological Protection, 2020
Abstract The radiation doses from natural radiation sources in Japan are reviewed using the latest knowledge. The United Nations Scientific Committee on the Effects of Atomic Radiation (UNSCEAR) and the Nuclear Safety Research Association report the annual effective doses from cosmic rays, terrestrial radiation, inhalation, and ingestion
Yasutaka Omori, Masahiro Hosoda, Fumiaki Takahashi, Tetsuya Sanada, Shigekazu Hirao, Koji Ono, Masahide Furukawa   +6 more
openaire   +2 more sources

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Cladoceran birth and death rates estimates [PDF]

, 1987
I. Birth and death rates of natural cladoceran populations cannot be measured directly. Estimates of these population parameters must be calculated using methods that make assumptions about the form of population growth.
Argentesi F., Caswell H., Cooper W.E., DeMott W.R., DeMott W.R., Dorazio R. M., Edmondson W.T., Edmondson W.T., Elstcr H.-J., Gehrs C.W., Hairstan N.G., Haney J. F., Keen R., Keyfitz N., Kirsch S., Lampert W., Leslie P.H., Lynch M., Lynch M., Muck P., Paloheimo J.E., Polishchuk L.V., Polishchuk L.V., Polishchuk L.V., Pollard J.H., Prepas E., Ricker W. E., Rigler F. H., Rigler F.H., Romanovski Y.E., Seitz A., Taylor B. E., Threlkeld S.T., Winberg G.G., Wright I.C.   +34 more
core   +1 more source

natural population analysis

, 2014
Citation: 'natural population analysis' in the IUPAC Compendium of Chemical Terminology, 3rd ed.; International Union of Pure and Applied Chemistry; 2006. Online version 3.0.1, 2019. 10.1351/goldbook.NT07080 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms. Requests
openaire   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Evolution of Biological Complexity [PDF]

, 1999
In order to make a case for or against a trend in the evolution of complexity in biological evolution, complexity needs to be both rigorously defined and measurable.
Britten, Britten, C. Adami, C. Ofria, Elena, Lenski, Mills, Schneider, Smith, T. C. Collier   +9 more
core   +6 more sources

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source