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Neurotrophins (NGF, BDNF, NT3, NT4) can decrease cell death, induce differentiation, as well as sustain the structure and function of neurons, which make them promising therapeutic agents for the treatment of neurodegenerative disorders. However, neurotrophins have not been very effective in clinical trials mostly because they cannot pass through the ...
Yoshiyasu, Fukuyama +2 more
openaire +2 more sources
Yoshiyasu, Fukuyama +2 more
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Application of omics- and multi-omics-based techniques for natural product target discovery
Biomedicine and Pharmacotherapy, 2021Dale Nagle, Weidong Zhang, Xin Luan
exaly
Genetic Biosensor Design for Natural Product Biosynthesis in Microorganisms
Trends in Biotechnology, 2020Matthew Chang, Hua Ling, Ryoma Miyake
exaly
A Natural Product Chemist's Guide to Unlocking Silent Biosynthetic Gene Clusters
Annual Review of Biochemistry, 2021Brett Covington +1 more
exaly
A natural product targets BRD4 to inhibit phase separation and gene transcription
IScience, 2022Yuhua Xue, Qiang Zhou, Xiang Gao
exaly
Click Chemistry in Natural Product Modification
Frontiers in Chemistry, 2021Hongtao Xu, Xiang Zhang, Bo Liu
exaly

