Pretubulysin derived probes as novel tools for monitoring the microtubule network via activity-based protein profiling and fluorescence microscopy [PDF]
Microtubules (mt) are highly dynamic polymers composed of alpha- and beta-tubulin monomers that are present in all dividing and non-dividing cells. A broad variety of natural products exists that are known to interfere with the microtubule network, by ...
Burkhart, Jens L.+7 more
core +1 more source
The tumor microenvironment is a dynamic, multifaceted complex system of interdependent cellular, biochemical, and biophysical components. Three‐dimensional in vitro models of the tumor microenvironment enable a better understanding of these interactions and their impact on cancer progression and therapeutic resistance.
Salma T. Rafik+3 more
wiley +1 more source
SYNTHETIC APPROACHES TO POLIFUNCTIONALIZED PERHYDRINDANES [PDF]
The current communication represents an extended abstract of the presentation delivered on the joint Moldo-Italian seminar “New frontiers in natural product chemistry”, held in the Institute of Chemistry, Academy of Sciences of Moldova on 31 September ...
Veaceslav Kulciţki
doaj
Undergraduate Entrepreneurial Intentions and Personal Attitude Towards Entrepreneurship in Natural Product Chemistry [PDF]
This study was carried out to determine the relationship between personal attitude and undergraduates’ entrepreneurial intentions towards entrepreneurship in natural product chemistry in Ignatius Ajuru University of Education Port Harcourt Rivers State ...
Worokwu, Chinda
core +2 more sources
Natural Product Nitric Oxide Chemistry: New Activity of Old Medicines [PDF]
The use of complementary and alternative medicine (CAM) as a therapy and preventative care measure for cardiovascular diseases (CVD) may prove to be beneficial when used in conjunction with or in place of conventional medicine.
Bryan, Nathan S.+3 more
core +3 more sources
Possible role of human ribonuclease dicer in the regulation of R loops
R loops play an important role in regulating key cellular processes such as replication, transcription, centromere stabilization, or control of telomere length. However, the unscheduled accumulation of R loops can cause many diseases, including cancer, and neurodegenerative or inflammatory disorders. Interestingly, accumulating data indicate a possible
Klaudia Wojcik+2 more
wiley +1 more source
The Chemistry of Natural Products related to Phenanthrene [PDF]
Louis Fieser
openalex +1 more source
Advanced glycation end products promote the release of endothelial cell‐derived mitocytosis
Under diabetic conditions, AGEs induce mitochondrial damage in HUVECs, activating migrasome‐mediated mitocytosis. Migrasomes encapsulate damaged mitochondria and are released into the extracellular space, facilitating intercellular mitochondrial transfer.
Rong Liu+6 more
wiley +1 more source
Marine Natural Products in Medicinal Chemistry [PDF]
An overview of the marine natural products (MNPs) field is shown, including an update of FDA-approved drugs and those in clinical trials that can be considered derivatives of MNPs. The importance of marine microorganisms in present studies and the application of emerging techniques and technologies to this field are highlighted.
openaire +3 more sources
UJI IRITASI DAN STABILITAS FISIKA KIMIA LIPSTIK DENGAN PEWARNA ALAMI EKSTRAK BUAH SALAM (Syzygium polyanthum (Wight) Walp.) [PDF]
Salam fruit (Syzygium polyanthum (Wight) Walp.) is one of the potential plants to be used as a natural colorant because it contains anthocyanin.
RAHMADHITA, MAYANG
core