Results 91 to 100 of about 9,230,804 (307)

Countercurrent chromatography in analytical chemistry (IUPAC technical report) [PDF]

open access: yes, 2009
© 2009 IUPACCountercurrent chromatography (CCC) is a generic term covering all forms of liquid-liquid chromatography that use a support-free liquid stationary phase held in place by a simple centrifugal or complex centrifugal force field. Biphasic liquid
Sutherland, IA   +37 more
core   +2 more sources

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

Shenrong Guben Huanshao Wan extract reduces Aβ-induced toxicity in the Caenorhabditis elegans model of Alzheimer’s disease via SKN-1/NRF2 pathway

open access: yesPharmacological Research - Modern Chinese Medicine
Introduction: Alzheimer's disease (AD) is a complex neurodegenerative disease leading to cognitive decline and behavioral changes. With known cure often aim to alleviate symptoms, it is crucial to find novel pharmacotherapies for AD treatment.
Hui-Jie Li   +10 more
doaj   +1 more source

Chemical synthesis and cytotoxicity of neo-glycolipids; rare sugar-glycerol-lipid compounds

open access: yesHeliyon, 2018
Rare sugars are defined as monosaccharides and their derivatives, which rarely exist in nature and have various beneficial effects on organisms, biomaterials and foods.
Keisuke Hirata   +4 more
doaj   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

Catalytic Markovnikov hydrophosphorylation of unactivated olefins via a radical-polar crossover rearrangement

open access: yesNature Communications
The phosphorylation of alkenes offers a diverse handle for obtaining organophosphoryls, but its regioselectivity still faces challenges, especially the radical Markovnikov hydrophosphorylation of alkenes.
Yi-Fan Li, Hong-Chen Wang, Bing Han
doaj   +1 more source

Natural products chemistry in the third millennium [PDF]

open access: yesChemistry Central Journal, 2007
The main directions of Natural Products Chemistry in the Third Millennium are summarized.
openaire   +2 more sources

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Bioinspired total syntheses of natural products: a personal adventure

open access: yesBeilstein Journal of Organic Chemistry
Bioinspired total synthesis represents an important concept to guide the designing of powerful synthetic strategies. Our group has a long-time interest and experience in designing synthetic strategies through analyzing the biosynthetic pathway of natural
Zhengyi Qin   +7 more
doaj   +1 more source

Application of Alginate-Based Edible Coating with Beeswax Addition on Minimally Processed Pears (Pyrus bretschneideri Rehd.)

open access: yesBiology, Medicine & Natural Product Chemistry
Pears, especially after being cut, tended to experience a decline in quality and damage such as enzymatic browning, moisture loss, and texture changes.
Maftukh Zaina Luthfiyyah   +3 more
doaj   +1 more source

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