Results 171 to 180 of about 12,894,217 (402)

Evolutionary dynamics of the chloroplast genome in Daphne (Thymelaeaceae): comparative analysis with related genera and insights into phylogenetics

FEBS Open Bio, EarlyView.
Comparative analysis of chloroplast genomes from 14 genera of Thymelaeaceae revealed variation in gene content, ranging from 128 to 142 genes, primarily influenced by IR expansion/contraction events and pseudogenization of ndhF, ndhI, and ndhG. Two large inversions were detected within the large single‐copy region, including a synapomorphic inversion ...
Abdullah, Hui Li, Rushan Yan, Chengyu Chen, Madiha Islam, Abdul Majid, Ibrar Ahmed, Parviz Heidari, Xiaoxuan Tian   +8 more
wiley   +1 more source

Consumers’ reasonings for intention to purchase natural personal care products in Indonesian market

, 2023
Margareth Setiawan, Rosita Widjojo, Doni Purnama Alamsyah   +2 more
openalex   +1 more source

Natural Product P57 Induces Hibernation-like State through Targeting Pyridoxal Kinase [PDF]

, 2022
Yongjun Dang, Ruina Wang, Lei Xiao, Jianpo Pan, Di Zhu, Jun Wang, Chengfeng Pei, Qinfeng Ma, Guangsen Bao, Ziruoyu Wang, Mengdi Zhu, Guoxiang Wang, Ling Gong, Qiuping Tong, Min Jiang, Junchi Hu, Miao He, Yun Wang, Tiejun li, Wei Li, Chunmin Liang, Zengxia Li, K. Dengke, Minjia Tan, Jun‐Yan Liu, Wei Jiang, Cheng Luo, Biao Yu   +27 more
openalex   +1 more source

The photoswitchable cannabinoid azo‐HU308 enables optical control of Ca2+ dynamics in INS‐1 β‐cells via off‐target effects on TRPC channels

FEBS Open Bio, EarlyView.
Light activation of the photoswitchable cannabinoid ligand azo‐HU308 triggers Ca2+ influx in pancreatic β‐cells through TRPC channels, independent of CB2 cannabinoid receptors. This reveals a non‐GPCR pathway for cannabinoid modulation of β‐cell Ca2+ dynamics and establishes azo‐HU308 as an optical tool to study cannabinoid signaling through TRP ...
Alexander E. G. Viray, James A. Frank
wiley   +1 more source

Identification of Antithrombotic Natural Products Targeting the Major Substrate Binding Pocket of Protein Disulfide Isomerase

, 2022
Chenghui Liang, Meiqin Cai, Yanyan Xu, Wei Fu, Juhong Wu, Yu‐Rong Liu, Xinyuan Liao, Jiamin Ning, Jinyu Li, Mingdong Huang, Cai Yuan   +10 more
openalex   +1 more source

DDX3X induces mesenchymal transition of endothelial cells by disrupting BMPR2 signaling

FEBS Open Bio, EarlyView.
Elevated DDX3X expression led to downregulation of BMPR2, a key regulator of endothelial homeostasis and function. Our co‐immunoprecipitation assays further demonstrated a molecular interaction between DDX3X and BMPR2. Notably, DDX3X promoted lysosomal degradation of BMPR2, thereby impairing its downstream signaling and facilitating endothelial‐to ...
Yu Zhang, Jing Wang, De‐Hui Qian, Yang‐Fan Lv, Tian‐Le Cheng, Da‐Peng Wang, Jing Zhang, Ye Fan   +7 more
wiley   +1 more source

Network analysis-guided drug repurposing strategies targeting LPAR receptor in the interplay of COVID, Alzheimer’s, and diabetes

Scientific Reports
The COVID-19 pandemic caused by the SARS-CoV-2 virus has greatly affected global health. Emerging evidence suggests a complex interplay between Alzheimer’s disease (AD), diabetes (DM), and COVID-19.
Dicson Sheeja Malar, Kanika Verma, Mani Iyer Prasanth, Tewin Tencomnao, James Michael Brimson   +4 more
doaj   +1 more source

Antibiofilm activity of a chionodracine‐derived peptide by NMR‐based metabolomics of cell‐free supernatant of Acinetobacter baumannii clinical strains

FEBS Open Bio, EarlyView.
KHS‐Cnd peptide is able to impair biofilm formation and disaggregate mature biofilms in Acinetobacter baumannii clinical isolates. Differences in extracellular metabolites reflect changes in biofilm metabolism due to KHS‐Cnd treatment. Among the differentially represented extracellular metabolites upon KHS‐Cnd treatment, the significantly altered ...
Fernando Porcelli, Enrico Landi, Francesco Maiurano, Irene Paris, Rosanna Papa, Marco Artini, Laura Selan, Stefano Borocci, Francesco Buonocore, Esther Imperlini   +9 more
wiley   +1 more source

In vitro and in silico anthelmintic and antibacterial activity of Rubus ellipticus leaf extracts

Discover Chemistry
Background Bacterial and helminthic evolution has resulted in a shocking development of antibiotic and anthelminthic resistance. Medicinal plants provide an encouraging source to develop new antibacterial and anthelmintic agents.
Deepak Kumar, Adarsh Kumar, Ankit Kumar Singh, Harshwardhan Singh, Pradeep Kumar   +4 more
doaj   +1 more source

Natural Products as Sources of New Drugs from 1981 to 2014.

Journal of Natural Products, 2016
D. Newman, G. Cragg
semanticscholar   +1 more source