Results 191 to 200 of about 12,894,217 (402)

Comparison of liquid chromatography-high-resolution tandem mass spectrometry (MS2) and multi-stage mass spectrometry (MS3) for screening toxic natural products

, 2023
Ruben Yiqi Luo, Kate Comstock, Caroline Ding, Alan H.B. Wu, Kara L. Lynch   +4 more
openalex   +1 more source

Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications

FEBS Open Bio, EarlyView.
This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley   +1 more source

Chemoenzymatic Synthesis of Thiazolyl Peptide Natural Products Featuring an Enzyme-Catalyzed Formal [4 + 2] Cycloaddition

, 2015
Walter J. Wever, Jonathan W. Bogart, Joshua A. Baccile, Andrew N. Chan, Frank C. Schroeder, Albert A. Bowers   +5 more
openalex   +1 more source

Synergistic Effects of Dietary Natural Products as Anti-Prostate Cancer Agents [PDF]

, 2015
Bao Vue, Sheng Zhang, Qiao‐Hong Chen
openalex   +1 more source

Natural products from plants and microorganisms: Novel therapeutics for chronic kidney disease via gut microbiota regulation [PDF]

, 2023
Zheng Lin, Mingjing Luo, Haokui Zhou, Jianping Chen   +3 more
openalex   +1 more source

Anticancer sensitivities and biological characteristics of HCT116 cells resistant to the selective poly(ADP‐ribose) glycohydrolase inhibitor

FEBS Open Bio, EarlyView.
We analyzed alterations of PAR metabolism‐related proteins in PARG inhibitor‐resistant HCT116RPDD cells. Although PARG levels remained unchanged, HCT116RPDD cells exhibited reduced PARP1 and ARH3 expression and elevated PAR levels. Interestingly, HCT116RPDD cells exhibited slightly elevated intracellular NAD+/NADH and ATP levels. Our findings suggest a
Kaede Tsuda, Yoko Ogino, Akira Sato
wiley   +1 more source

In vitro and in silico anthelminthic evaluations of the extracts of Aglaia Elaea gnoidea leaves against Pheretima posthuma

Discover Chemistry
Context Helminth infections remain a significant public health challenge, particularly in tropical regions, where they are among the most neglected tropical diseases.
Sai Eswar, Adarsh Kumar, Ankit Kumar Singh, Harshwardhan Singh, Pradeep Kumar   +4 more
doaj   +1 more source

The antidepressant effects of kaji-ichigoside F1 via activating PPAR-γ/CX3CR1/Nrf2 signaling and suppressing NF-κB/NLRP3 signaling pathways

Frontiers in Pharmacology
IntroductionDepression is a mental illness closely associated with neurological damage and is characterised by high rates of suicide and mood changes. As a traditional medicinal plant, Rosa roxburghii Tratt has been widely used since ancient times in the
Maoyang Huang, Maoyang Huang, Faju Chen, Faju Chen, Lang Zhou, Qing Zhang, Li Wang, Liangqun Li, Lishou Yang, Ming Gao, Lilang Li, Yu Wang, Juan Yang, Guanping Yao, Qiji Li, Qiji Li, Xiaosheng Yang, Xiaosheng Yang   +17 more
doaj   +1 more source

Models of drug-induced liver injury for evaluation of phytotherapeutics and other natural products

, 2013
Hartmut Jaeschke, C. David Williams, Mitchell R. McGill, Yuchao Xie, Anup Ramachandran   +4 more
openalex   +1 more source

Natural products as sources of new drugs over the 30 years from 1981 to 2010.

Journal of Natural Products, 2012
D. Newman, G. Cragg
semanticscholar   +1 more source