Results 71 to 80 of about 7,916,773 (303)
Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy
FEBS Letters, EarlyView.The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley +1 more source
Natural resistance mechanisms of plants to viruses
, 2005 In this synopsis several mechanisms of natural resistance of plants to viral infections is outlined.
Loebenstein, G., G. Loebenstein
core +1 more source
Unlocking the potential of cell‐permeable nanobodies for intracellular applications
FEBS Letters, EarlyView.This review outlines current strategies for delivery of nanobodies into cells and highlights recent examples of functional applications. By addressing and manipulating intracellular targets, these molecules hold great potential for treating cancer, respiratory diseases and neurological disorders, making this a vibrant area of research in the biomedical
Mariona Gené‐Verdés +2 more
wiley +1 more source
Chemical defense mechanisms of soybean genotypes against lepidopterans
Frontiers in Plant ScienceSoybean (Glycine max [L.] Merrill) is one of the world’s most important agricultural crops, playing a strategic role in global protein and lipid production. However, its productivity is severely constrained by defoliating lepidopterans such as Anticarsia
Josicleia Oliveira Costa +5 more
doaj +1 more source
HXNBR Coating for Improving Aging Resistance of Natural Rubber Products
, 2006 HXNBR (Hydrogenated Carboxylated Nitrile Rubber) has very good heat ageing resistance and oil resistance. A novel accelerator system is designed to bring about the vulcanization of HXNBR at room temperature. The room temperature cured samples showed good
Rani Joseph
core +1 more source
Comparing the paths of Hedgehog release in artificial and natural settings
FEBS Letters, EarlyView.Hh morphogens require solubilization factors to overcome their tight association with the plasma membrane and signal to distant cells, but the precise functions of these factors are controversial. Here, we use published in vivo observations as the most relevant evidence to test their suggested functions and discuss contradictions and gaps between in ...
Janna Puschmann, Kay Grobe
wiley +1 more source
Microbiology SpectrumMycobacterium tuberculosis (Mtb), the cause of tuberculosis, kills over 1 million people worldwide each year. Mtb is classified into 10 distinct lineages, each harboring unique genetic changes that influence its survival, virulence, and transmissibility.
Ashleigh Cheyne +7 more
doaj +1 more source
How structural disorder and polyelectrolyte properties of prothymosin α enable its large interactome
FEBS Letters, EarlyView.In this review, complexes of the fully disordered and highly negatively charged prothymosin α are collected, described, and discussed. Linked to its poly‐electrostatic character, prothymosin α engages a large interactome through multiple different binding modes ranging from fully disordered complexes to short linear motif (SLiM)‐driven interactions ...
Ketty C. Tamburrini +3 more
wiley +1 more source
Sidebar: Importance of herbicide resistance in weeds of natural areas [PDF]
, 2014 Worldwide, the majority of the plant species that are developing herbicide resistance are those that occur as weeds in agricultural environments, on roadsides and in other rights-of-way.
Joseph DiTomaso, DiTomaso, Joseph
core +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source