Results 71 to 80 of about 2,859,789 (309)

Natural Inhibitors of Snake Venom Metalloendopeptidases: History and Current Challenges

open access: yesToxins, 2016
The research on natural snake venom metalloendopeptidase inhibitors (SVMPIs) began in the 18th century with the pioneering work of Fontana on the resistance that vipers exhibited to their own venom.
Viviane A. Bastos   +4 more
doaj   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Reacciones y alteraciones del sistema inmune durante la infección por el VIH-1

open access: yesInfectio, 2006
El síndrome de inmunodeficiencia adquirida, o sida, es el desenlace final de la infección crónica con el virus de inmunodeficiencia humana tipo 1 (VIH-1) y se asocia con la aparición de enfermedades oportunistas, procesos oncogénicos y enfermedades ...
CARLOS JULIO MONTOYA GUARÍN   +2 more
doaj  

Impaired decidual natural killer cell regulation of vascular remodelling in early human pregnancies with high uterine artery resistance [PDF]

open access: yes, 2012
During human pregnancy, natural killer (NK) cells accumulate in the maternal decidua, but their specific roles remain to be determined. Decidual NK (dNK) cells are present during trophoblast invasion and uterine spiral artery remodelling.
Cartwright, JE   +6 more
core   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

Using porous metals to enhance heat transfer in phase change materials (PCMs) [PDF]

open access: yes, 2011
Heat transfer enhancement mechanism of Phase Change Materials (PCMs) by high-porosity metal foams was investigated in this study. The Darcy-Brinkman-Forchheimer modified flow model was employed in the numerical simulations to consider the non-Darcy ...
Tian, Y. (Yuan), Zhao, Changying
core  

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

open access: yesFEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li   +8 more
wiley   +1 more source

Chemical defense mechanisms of soybean genotypes against lepidopterans

open access: yesFrontiers in Plant Science
Soybean (Glycine max [L.] Merrill) is one of the world’s most important agricultural crops, playing a strategic role in global protein and lipid production. However, its productivity is severely constrained by defoliating lepidopterans such as Anticarsia
Josicleia Oliveira Costa   +5 more
doaj   +1 more source

Detection of bacterial sulfatase activity through liquid- and solid-phase colony-based assays

open access: yesAMB Express, 2017
Bacterial arylsulfatases are crucial to biosynthesis in many microorganisms, as bacteria often utilize aryl sulfates as a source of sulfur. The bacterial sulfatases are associated with pathogenesis and are applied in many areas such as industry and ...
Hey Young Yoon   +3 more
doaj   +1 more source

The effect of combined sewer overflow (CSO) on the abundance of antibiotic resistant bacteria in the James River [PDF]

open access: yes, 2017
Antibiotics have been used to treat bacterial infections worldwide since their discovery in the early 20th century and are vital to human health. Unfortunately, the heavy use of antibiotics has led to the increased natural selection of antibiotic ...
Franklin, Rima B   +2 more
core   +1 more source

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