The integrated concept of disease resistance; a new view including horizontal and vertical resistance in plants [PDF]
Horizontal, uniform, race-non-specific or stable resistance can be discerned according to Van der Plank, from vertical, differential, race-specific or unstable resistance by a test in which a number of host genotypes (cultivars or clones) are tested ...
Parlevliet, J.E., Zadoks, J.C.
core +2 more sources
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui +10 more
wiley +1 more source
Digital twins to accelerate target identification and drug development for immune‐mediated disorders
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley +1 more source
Acaricide resistance and genetic affinities of some selected populations of Tetranychus urticae Koch in New Zealand : a thesis presented in partial fulfilment of the requirements for the degree of Master of Science (Horticultural) in Entomology at Massey University [PDF]
A study of resistance to acaricides in a number of populations of the two-spotted spider mite, Tetranychus urticae, in New Zealand had been carried out.
Ong, S. H.
core
LPS resistance of SPRET/Ei mice is mediated by Gilz, encoded by the Tsc22d3 gene on the X chromosome [PDF]
Natural variation for LPS-induced lethal inflammation in mice is useful for identifying new genes that regulate sepsis, which could form the basis for novel therapies for systemic inflammation in humans.
Beaulieu E +12 more
core +2 more sources
Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková +3 more
wiley +1 more source
СЕЗОННАЯ ДИНАМИКА ФАКТОРОВ ЕСТЕСТВЕННОЙ РЕЗИСТЕНТНОСТИ
The evaluation of season dynamics of natural resistance factors is conducted.
doaj
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
РЕЗИСТЕНТНОСТЬ ПОМЕСНЫХ ПОРОСЯТ РАЗЛИЧНЫХ ГЕНОТИПОВ ПО ГЕНУ RYR-1
authors define level of natural resistance of pigs of different genotypes on gene RYR-1 at carrying out of two - and three-pedigree industrial crossing.
doaj
Are zooplankton invasions in constructed waters facilitated by simple communities? [PDF]
The invasion of non-indigenous species is considered to be one of the leading causes of biodiversity loss globally. My research aimed to determine if constructed water bodies (e.g., water supply reservoirs, dams and ponds) were invaded by zooplankton ...
Parkes, Samantha Maree
core +1 more source

