Results 111 to 120 of about 77,443 (304)

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

open access: yesFEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho   +4 more
wiley   +1 more source

L'enseignement des sciences naturelles au XIXe siècle dans ses liens à d'autres disciplines / The teaching of natural sciences in the 19th century in its links to other disciplines

open access: yes, 2002
SUMMARY. — Natural science was a for a long time associated with physical science on account of the agrégation examination and the place alloted to mineralogy in the science curriculum.
Hulin, Nicole
core   +1 more source

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

open access: yesFEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento   +6 more
wiley   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

Caring for Weak Ties - the Natural History Museum as a Place of Encounter Between Amateur and Professional Science [PDF]

open access: yes
This article is concerned with a community of practitioners that does not hold together well: amateur scientists. It examines the interrelationships between amateurs and professionals in a museum of natural history and focuses, in particular, upon two ...
Morgan Meyer
core  

Toward a feminist natural science: linking theory and practice

open access: yes, 1998
In this paper I tackle the gulf between feminist epistemologies of science and the practice of the natural sciences. I begin by considering the feminist epistemologies of science, focusing in particular on standpoint theories and objectivity in the work ...
Kerr, E. Anne
core   +1 more source

Ecospiritual Praxis: Cultivating Connection to Address the Climate Crisis

open access: yesReligions
This article suggests ecospirituality as a connection point between religion, science, and other disciplines, as well as the relationships between people, the land and waters, the community of all life, and the Divine.
Cherice Bock
doaj   +1 more source

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

open access: yesFEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin   +3 more
wiley   +1 more source

CAUSE-EFFECT DISORDERS IN THE UNDERSTANDING OF PROCESSES REVEALEDIN TEACHING NATURAL SCIENCE DISCIPLINES TO STUDENTS MAJORING IN THE HUMANITIES

open access: yesВестник Кемеровского государственного университета, 2014
The paper describes several principals of a social-and-educational system functioning on the example of the system of “Natural Science education”. Some problems in the functioning of this system are examinedon the basis of synergic and information ...
T. Yu. Drobchik, B. P. Nevzorov
doaj  

Sacrificing Natural Kinds

open access: yesArs & Humanitas
The article reevaluates Jerry Fodor’s key argument for the autonomy of the special sciences, which rests on the notion of multiple realization and the claim that special science predicates must be natural kinds.
Tadej Todorović, Janez Bregant
doaj   +1 more source

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