Results 111 to 120 of about 728,426 (302)

Life sciences space station planning document: A reference payload for the exobiology research facilities [PDF]

open access: yes
The Cosmic Dust Collection and Gas Grain Simulation Facilities represent collaborative efforts between the Life Sciences and Solar System Exploration Divisions designed to strengthen a natural exobiology/Planetary Sciences connection.

core   +1 more source

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

open access: yesFEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková   +3 more
wiley   +1 more source

Combined 5‐aminolevulinic acid and ferric ammonium citrate treatment promotes hair follicle growth by activating dermal papilla cells

open access: yesFEBS Open Bio, EarlyView.
5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley   +1 more source

Scientific knowledge and knowledge needs in climate adaptation policy: a case study of diverse mountain regions [PDF]

open access: yes, 2017
Mountain ecosystems around the world are recognized to be among the most vulnerable to the impacts of climate change. The need to develop sound adaptation strategies in these areas is growing.
Huggel, Christian   +2 more
core  

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

open access: yesFEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke   +4 more
wiley   +1 more source

Theoretical perspectives in purchasing and supply chain management: an analysis of the literature [PDF]

open access: yes, 2010
The research presented in this paper is work-in-progress and aims to investigate to what extent purchasing and supply chain management (SCM), as a relatively new area of academic enquiry, is ready or able to join the select group of modern scientific ...
Chicksand, Daniel   +5 more
core  

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

The skills required for transition to university and study in biological sciences: A student perspective

open access: yesFEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

The Lens of Faith [PDF]

open access: yes, 2007
In lieu of an abstract, below is the essay\u27s first paragraph. For seven years during the nineties, I taught a course at St. Michael’s College in the University of Toronto called Christianity and Science.
Lococo, Donald J.
core   +1 more source

Ecospiritual Praxis: Cultivating Connection to Address the Climate Crisis

open access: yesReligions
This article suggests ecospirituality as a connection point between religion, science, and other disciplines, as well as the relationships between people, the land and waters, the community of all life, and the Divine.
Cherice Bock
doaj   +1 more source

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