Results 121 to 130 of about 77,443 (304)

Versatile vector tools for efficient protein screening across multiple expression systems

open access: yesFEBS Open Bio, EarlyView.
A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu   +5 more
wiley   +1 more source

Types and role of school learning tasks in natural science disciplines

open access: yesVestnik of Kostroma State University. Series: Pedagogy. Psychology. Sociokinetics
The article reveals the main approaches to the study of educational tasks, their types and didactic functions. The specification of the types of school learning tasks in the natural sciences, the author's vision of such typologization, the relationship between the types of learning tasks in the natural sciences and their didactic functions, as well as ...
openaire   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

open access: yesFEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin   +12 more
wiley   +1 more source

Web Science and the two (hundred) cultures: representation of disciplines publishing in Web Science

open access: yes, 2013
Web Science is an interdisciplinary field. Motivated by the unforeseen scale and impact of the web, it addresses web related research questions in a holistic manner, incorporating epistemologies from a broad set of disciplines.
Hooper, Clare   +2 more
core  

Emerging insights into CC and CXC chemokines and their receptors in Mycobacterium tuberculosis infection

open access: yesFEBS Open Bio, EarlyView.
The dual roles of CC and CXC chemokines in distinguishing active, latent, and subclinical tuberculosis were reviewed, along with an evaluation of their potential as diagnostic biomarkers and therapeutic targets to advance precision medicine in tuberculosis management. The graphical abstract was generated with AI assistance (Gemini 3.0).
Xuying Yin, Dangsheng Xiao, Jiezuan Yang
wiley   +1 more source

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

open access: yesFEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão   +3 more
wiley   +1 more source

Natural &/or Artificial Minds: 1st Online Graduate Conference of the Italian Association for Cognitive Science (AISC)

open access: yes, 2021
Since its early days, cognitive science has been characterized by analogies between the human and other minds, be them (non-human) biological or artificial. The consideration of non-human minds has played, and still plays, its role in many ways.
Marco Marini   +5 more
core  

Forming of Students Valeological Culture in Studying of Natural-Science Disciplines (by Example of Physics Course)

open access: yesНаучный диалог, 2017
The article is devoted to the problem of valeological culture education in the process of studying of natural-science disciplines at school. The importance of developing skills aimed at the development of a healthy lifestyle in the process of realization
E. V. Ermakova   +3 more
doaj  

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

Cross-curricular goals and raising the relevance of science education

open access: yes, 2017
‘Relevance’ is one of the most commonly used terms when it comes to reforms in science education. The term is used in manifold ways. It can be understood – among other things – as meeting an interest, fulfilling needs or contributing to intellectual ...
Nadja Belova   +21 more
core   +1 more source

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