Results 101 to 110 of about 12,832,013 (404)

Deterministic chaos theory and forecasting in Social Sciences. Contribution to the discussion [PDF]

open access: yes, 2018
Forecasting social phenomena may be hampered in many ways. This is because in nature of these phenomena lies strong and multilateral connection with other social phenomena; but not only – also physical and biological (natural) ones.
Donaj, Łukasz
core   +2 more sources

Strength through diversity: how cancers thrive when clones cooperate

open access: yesMolecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken   +3 more
wiley   +1 more source

A two-component cocktail of engineered DIII nanoparticles elicits broadly neutralizing antibody responses against dengue virus in mice

open access: yesiScience
Summary: Dengue virus (DENV) is a mosquito-transmitted flavivirus; there are four serotypes (DENV1-4) that co-circulate globally. Primary infection causes self-limiting febrile illness, but secondary infection by a heterologous serotype can predispose to
Margarette C. Mariano   +10 more
doaj   +1 more source

Communicating the social sciences [PDF]

open access: yes, 2008
This chapter reviews the sparse and somewhat scattered research literature that has specifically addressed the public communication of the social sciences (PCSS).
Cassidy, A
core  

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

Shaping electrospray plume with convergent sound beams

open access: yesiScience
Summary: Electrospray ionization (ESI) is one of the mainstream ionization techniques for mass spectrometry (MS) nowadays. Here, we present a new variant of ESI-MS setup, in which an electrospray emitter points to the mass spectrometer’s orifice while ...
Yu-Hao Chen   +2 more
doaj   +1 more source

The integrative framework for the behavioural sciences has already been discovered, and it is the adaptationist approach [PDF]

open access: yes, 2007
The adaptationist framework is necessary and sufficient for unifying the social and natural sciences. Gintis’s “beliefs, preferences, and constraints” (BPC) model compares unfavorably to this framework because it lacks criteria for determining special ...
Brown, WM, Curry, OS, Price, M
core   +1 more source

TREX1, a predator for treating MSI‐H tumors?

open access: yesMolecular Oncology, EarlyView.
Immunotherapy benefits many patients; yet, some with MSI‐H tumors remain unresponsive despite their high immunogenicity. Xu et al. reveal that TREX1 enables immune evasion by degrading cytosolic DNA and suppressing cGAS–STING–IFN‐I signaling. TREX1 loss restores DNA sensing, increases CD8+ T and NK cell infiltration, and boosts antitumor immunity ...
Elena Benidovskaya   +2 more
wiley   +1 more source

Time-domain adjoint optimization for metalens design toward enhanced broadband efficiency and uniformity

open access: yesiScience
Summary: We propose a time-domain adjoint optimization method for achromatic metalens design, achieving high efficiency and near-uniform spectral response.
Mingyu Park   +2 more
doaj   +1 more source

Digital Preservation and Access of Natural Resources Documents [PDF]

open access: yes, 2017
Digitization and preservation of natural resource documents were reviewed and the current status of digitization presented for a North American university.
Bullard, Steven H   +4 more
core   +2 more sources

Home - About - Disclaimer - Privacy