Results 101 to 110 of about 5,166,609 (350)

Therapeutic applications of a novel humanized monoclonal antibody targeting chemokine receptor CCR9 in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
C–C chemokine receptor type 9 (CCR9) is an immune checkpoint in pancreatic ductal adenocarcinoma (PDAC). Novel anti‐CCR9 antibody SRB2 was evaluated in combination with cytotoxic chemotherapy in PDAC cells, patient‐derived organoids, patient‐derived xenografts, and humanized mouse models.
Hannah G. McDonald   +18 more
wiley   +1 more source

Thomas Torrance\u27s Reformulation of Karl Barth\u27s Christological Rejection of Natural Theology [PDF]

open access: yes, 2001
Karl Barth is widely noted for his antipathy to all forms of natural theology. Indeed, the results of Barth’s Christocentricity have made his name synonymous with the negation of all divine revelation apart from Christ, the one Word of God.
Morrison, John D.
core   +1 more source

Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias   +12 more
wiley   +1 more source

Positioning, navigation, and timing on the Moon and Mars with galactic cosmic rays

open access: yesiScience
Summary: The muometric wireless navigation system (MuWNS) is a technology enabling signal reception for machine controlling and communication systems underground where a radio or GPS signal would normally be lost.
G. Leone   +14 more
doaj   +1 more source

Tumor clusters with divergent inflammation and human retroelement expression determine the clinical outcome of patients with serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Analysis of treatment‐naïve high‐grade serous ovarian carcinoma (HGSOC) and control tissues for ERVs, LINE‐1 (L1), inflammation, and immune checkpoints identified five clusters with diverse patient recurrence‐free survivals. An inflammation score was calculated and correlated with retroelement expression, where one novel cluster (Triple‐I) with high ...
Laura Glossner   +6 more
wiley   +1 more source

Flexible terahertz beam manipulation and convolution operations in light-controllable digital coding metasurfaces

open access: yesiScience
Summary: The development of coding metasurface opens an important development direction for beam modulator components. However, the lack of dynamic tunability is a major obstacle to the development and practicality of terahertz coding metasurface.
Min Jia   +4 more
doaj   +1 more source

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