Results 101 to 110 of about 7,095,217 (351)

The role of natural selection in human evolution – insights from Latin America

open access: yesGenetics and Molecular Biology
A brief introduction considering Darwin's work, the evolutionary synthesis, and the scientific biological field around the 1970s and subsequently, with the molecular revolution, was followed by selected examples of recent investigations dealing with the ...
Francisco M. Salzano
doaj   +1 more source

Identifying Potential Plasmodium vivax Sporozoite Stage Vaccine Candidates: An Analysis of Genetic Diversity and Natural Selection

open access: yesFrontiers in Genetics, 2018
Parasite antigen genetic diversity represents a great obstacle when designing a vaccine against malaria caused by Plasmodium vivax. Selecting vaccine candidate antigens has been focused on those fulfilling a role in invasion and which are conserved, thus
Diego Garzón-Ospina   +5 more
doaj   +1 more source

Pericytes change function depending on glioblastoma vicinity: emphasis on immune regulation

open access: yesMolecular Oncology, EarlyView.
Pericytes alter their transcriptome depending on their proximity to the tumor core. In the tumor core, pericytes display a more active state with higher communication strength but with lower immune activation potential and a shift toward extracellular matrix production.
Carolina Buizza   +5 more
wiley   +1 more source

Effect of natural selection on common bean (Phaseolus vulgaris) microsatellite alleles

open access: yesGenetics and Molecular Biology, 2006
The effect of natural selection on microsatellite simple sequence repeat (SSR) alleles was investigated in two distinct common bean (Phaseolus vulgaris) generations (F8 and F24) derived from the cross between the P.
Taislene Butarello Rodrigues   +1 more
doaj   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

open access: yesMolecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou   +5 more
wiley   +1 more source

Practical challenges in data‐driven interpolation: Dealing with noise, enforcing stability, and computing realizations

open access: yesInternational Journal of Adaptive Control and Signal Processing, EarlyView., 2023
Summary In this contribution, we propose a detailed study of interpolation‐based data‐driven methods that are of relevance in the model reduction and also in the systems and control communities. The data are given by samples of the transfer function of the underlying (unknown) model, that is, we analyze frequency‐response data.
Quirin Aumann, Ion Victor Gosea
wiley   +1 more source

Panmixia and Natural Selection [PDF]

open access: yesNature, 1894
MR. AVELDON'S letter on this subject, in NATURE of May 3, calls, I think, for a few farther observations. He first criticises the statement that “the survival-mean must, on cessation of selection, fall to the birth-mean,” by showing that there are probably cases in nature in which the survival and birth-means may coincide, owing to the removal by ...
openaire   +2 more sources

Phytoremediation: mechanisms, plant selection and enhancement by natural and synthetic agents

open access: yesEnvironmental Advances, 2022
Arjun Kafle   +5 more
semanticscholar   +1 more source

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