Results 81 to 90 of about 14,815,342 (343)
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
“The Case for Natural Selection” [PDF]
Nature, 1954 THAT my review of Dr. Huxley's book should be regarded as a matter of “major concern to general biological theory” is a sobering thought. It just shows how careful one must be in approaching the preserves of evolutionary genetics.
openaire +1 more source
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Spatial heterogeneity, frequency-dependent selection and polymorphism in host-parasite interactions
BMC Evolutionary Biology, 2011 Background Genomic and pathology analysis has revealed enormous diversity in genes involved in disease, including those encoding host resistance and parasite effectors (also known in plant pathology as avirulence genes).
Tellier Aurélien, Brown James KM
doaj +1 more source
Artificial molecular machines and motors—Design and control of nanoscale motion
FEBS Letters, EarlyView.Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley +1 more source
Other title: Title from HTML header (viewed Nov. 9, 2011): Judicial Selection Commission
, 2017 Updated irregularly; Began in 2002?; Title from main search screen (publisher's Web site, viewed Nov. 9, 2011).; At head of title: State of Connecticut.; Harvested from the web on 5/8/17Official website of the Connecticut Judicial Selection Commission ...
core +1 more source
, 2017 Invited artist page contribution to Natural Selection magazine, curated by Judy Darragh, Lousie Menzies and Fiona Gilmore.http://librarysearch.auckland.ac.nz/UOA2_A:Combined_Local ...
Jack, FA
core
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
On the Unit of Selection in Sexual Populations
, 2005 Evolution by natural selection is a process of variation and selection acting on replicating units. These units are often assumed to be individuals, but in a sexual population, the largest reliably-replicated unit on which selection can act is a small ...
Richard A. Watson, Watson, Richard A.
core +2 more sources