Results 81 to 90 of about 7,938,696 (303)
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Optimality and Natural Selection in Markets [PDF]
Evolutionary arguments are often used to justify the fundamental behavioral postulates of competive equilibrium. Economists such as Milton Friedman have argued that natural selection favors profit maximizing firms over firms engaging in other behaviors ...
Lawrence E. Blume, David Easley
core
Artificial selection, sexual selection, natural selection [PDF]
, 2011 Fil: Ginnobili, Santiago. Universidad de Buenos Aires; Argentina.Fil: Ginnobili, Santiago. Universidad Nacional de Quilmes; Argentina.Fil: Ginnobili, Santiago.
Ginnobili, Santiago
core +2 more sources
PlantsAreca palm velarivirus 1 (APV1), the causal agent of yellow leaf disease (YLD), poses a serious threat to the economically important areca palm industry in the Hainan Province, China, yet its evolutionary dynamics remain poorly understood.
Xiaoqing Niu +5 more
doaj +1 more source
Insights into the genetic and host adaptability of emerging porcine circovirus 3
Virulence, 2018 Porcine circovirus 3 (PCV3) was found to be associated with reproductive disease in pigs, and since its first identification in the United States, it subsequently spread worldwide, especially in China, where it might pose a potential threat to the ...
Gairu Li +9 more
doaj +1 more source
Increase in Complexity and Information through Molecular Evolution
Entropy, 2016 Biological evolution progresses by essentially three different mechanisms: (I) optimization of properties through natural selection in a population of competitors; (II) development of new capabilities through cooperation of competitors caused by ...
Peter Schuster
doaj +1 more source
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Evolutionary insights into duffy gene in mammalian taxa with comparative genetic analysis [PDF]
Journal of Vector Borne Diseases, 2009 Background & objectives: Evolutionary analyses of genes conserved across taxa are keys tounderstand the complexity of gene and genome variation. Since malaria is a highly infectioushuman disease and its susceptibility in human is genetically controlled ...
Gauri Awasthi, Aditya P. Dash
doaj
Molecular Oncology, EarlyView.Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
Ecology and EvolutionMacropsini is a tribe of Eurymelinae in the family Cicadellidae that is widely distributed worldwide. Still, its taxonomic status has been unstable, and the classification of certain clades at the genus level has been controversial. The aim of this study
Meishu Guo +7 more
doaj +1 more source