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On the Nature of Natural Selection
Some philosophers, known as statisticalists, claim that the concept of natural selection, as it is normally presented in population genetics, is statistical in character and cannot be construed in causal terms. On the contrary, other philosophers, known as causalists, argue against the statistical view and reaffirm the causal interpretation of natural ...
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Natural Selection as Coarsening [PDF]
Analogies between evolutionary dynamics and statistical mechanics, such as Fisher's second-law-like "fundamental theorem of natural selection" and Wright's "fitness landscapes", have had a deep and fruitful influence on the development of evolutionary theory. Here I discuss a new conceptual link between evolution and statistical physics.
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Predator-driven natural selection on risk-taking behavior in anole lizards
Predation favors the unadventurous Selection is likely to shape behavior by acting on behavioral differences between individuals. Testing this idea has been challenging. Lapiedra et al.
O. Lapiedra +4 more
semanticscholar +1 more source
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Conceptual models of adaptive divergence and ecological speciation in sympatry predict differential resource use, phenotype–environment correlations, and reduced gene flow among diverging phenotypes.
Matthew K. Brachmann +3 more
doaj +1 more source
The Usutu virus (USUV) is an emerging arbovirus virus maintained in the environment of Afro-Eurasia via a bird-mosquito-bird enzootic cycle and sporadically infected other vertebrates.
Jianglin Zhou +3 more
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BackgroundHow acceptance of evolution relates to understanding of evolution remains controversial despite decades of research. It even remains unclear whether cultural/attitudinal factors or cognitive factors have a greater impact on student ability to ...
M. E. Barnes +4 more
semanticscholar +1 more source

