Results 41 to 50 of about 1,205,213 (312)
Are Random Drift and Natural Selection Conceptually Distinct? [PDF]
, 2001 The latter half of the twentieth century has been marked by debates in evolutionary biology over the relative significance of natural selection and random drift: the so-called neutralist/selectionist debates.
Millstein, Roberta L.
core
História, Ciências, Saúde: Manguinhos, 2001 A teoria da evolução por seleção natural de Charles Darwin, ao relacionar os seres vivos genealogicamente, interpreta as espécies e sua fantástica diversidade como uma história de transformações lentas e graduais.
Ricardo Waizbort
doaj +1 more source
Genomic Legacies of Ancient Adaptation Illuminate GC-Content Evolution in Bacteria
Microbiology Spectrum, 2023 Bacterial evolution is characterized by strong purifying selection as well as rapid adaptive evolution in changing environments. In this context, the genomic GC content (genomic GC) varies greatly but presents some level of phylogenetic stability, making
Wenkai Teng +3 more
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On the Nature of Natural Selection
, 2018 Some philosophers, known as statisticalists, claim that the concept of natural selection, as it is normally presented in population genetics, is statistical in character and cannot be construed in causal terms. On the contrary, other philosophers, known as causalists, argue against the statistical view and reaffirm the causal interpretation of natural ...
openaire +2 more sources
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Frontiers in Genetics, 2022 The major histocompatibility complex (MHC) is an important genomic region for adaptive immunity and has long been studied in ecological and evolutionary contexts, such as disease resistance and mate and kin selection.
Daren C. Card +8 more
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FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Natural Selection _In Utero_ Contributes to the Male Longevity Deficit in Contemporary Human Populations [PDF]
, 2009 Much literature invokes natural selection to explain the pervasive deficit in the average lifespan of men compared to women.^1^ The explanation assumes that mothers, not fathers, provisioned children over much of human existence, and that women who lived
Ralph Catalano
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Material selection of natural fibre using a grey relational analysis (GRA) approach [PDF]
, 2022 Numerous situations in daily life necessitate a decision. Several of them entail selecting the best option from a number of available options. In many such cases, no single solution is optimal for all of the performance characteristics.
Mohamed Yusoff, M. Z. +3 more
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Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source