Results 31 to 40 of about 7,938,696 (303)

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

Are Random Drift and Natural Selection Conceptually Distinct? [PDF]

open access: yes, 2001
The latter half of the twentieth century has been marked by debates in evolutionary biology over the relative significance of natural selection and random drift: the so-called neutralist/selectionist debates.
Millstein, Roberta L.
core  

Natural Selection and Morality [PDF]

open access: yesIdeas y Valores, 2006
Resumen:En este ensayo abordo los intentos, relativamente recientes, de dar una explicación de la moralidad como adaptación por selección natural. Mi exposición tiene una introducción y cuatro partes: en la primera explico en qué consiste la paradoja del
Alejandro Rosas
doaj  

Teoria social e biologia: perspectivas e problemas da introdução do conceito de história nas ciências biológicas Social Theories and Biology: perspectives and problems of the introduction of the historical concept into biological sciences

open access: yesHistória, Ciências, Saúde: Manguinhos, 2001
A teoria da evolução por seleção natural de Charles Darwin, ao relacionar os seres vivos genealogicamente, interpreta as espécies e sua fantástica diversidade como uma história de transformações lentas e graduais.
Ricardo Waizbort
doaj   +1 more source

Structure and evolution of the squamate major histocompatibility complex as revealed by two Anolis lizard genomes

open access: yesFrontiers in Genetics, 2022
The major histocompatibility complex (MHC) is an important genomic region for adaptive immunity and has long been studied in ecological and evolutionary contexts, such as disease resistance and mate and kin selection.
Daren C. Card   +8 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Natural Selection as a Population-Level Causal Process [PDF]

open access: yes, 2006
Recent discussions in the philosophy of biology have brought into question some fundamental assumptions regarding evolutionary processes, natural selection in particular.
Millstein, Roberta L.
core  

On the Nature of Natural Selection

open access: yes, 2018
Some philosophers, known as statisticalists, claim that the concept of natural selection, as it is normally presented in population genetics, is statistical in character and cannot be construed in causal terms. On the contrary, other philosophers, known as causalists, argue against the statistical view and reaffirm the causal interpretation of natural ...
openaire   +2 more sources

Natural Selection as Coarsening [PDF]

open access: yesJournal of Statistical Physics, 2017
Analogies between evolutionary dynamics and statistical mechanics, such as Fisher's second-law-like "fundamental theorem of natural selection" and Wright's "fitness landscapes", have had a deep and fruitful influence on the development of evolutionary theory. Here I discuss a new conceptual link between evolution and statistical physics.
openaire   +4 more sources

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

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