Results 31 to 40 of about 1,099,029 (313)

Natural Selection and Morality [PDF]

open access: yesIdeas y Valores, 2006
Resumen:En este ensayo abordo los intentos, relativamente recientes, de dar una explicación de la moralidad como adaptación por selección natural. Mi exposición tiene una introducción y cuatro partes: en la primera explico en qué consiste la paradoja del
Alejandro Rosas
doaj  

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Teoria social e biologia: perspectivas e problemas da introdução do conceito de história nas ciências biológicas Social Theories and Biology: perspectives and problems of the introduction of the historical concept into biological sciences

open access: yesHistória, Ciências, Saúde: Manguinhos, 2001
A teoria da evolução por seleção natural de Charles Darwin, ao relacionar os seres vivos genealogicamente, interpreta as espécies e sua fantástica diversidade como uma história de transformações lentas e graduais.
Ricardo Waizbort
doaj   +1 more source

Genomic Legacies of Ancient Adaptation Illuminate GC-Content Evolution in Bacteria

open access: yesMicrobiology Spectrum, 2023
Bacterial evolution is characterized by strong purifying selection as well as rapid adaptive evolution in changing environments. In this context, the genomic GC content (genomic GC) varies greatly but presents some level of phylogenetic stability, making
Wenkai Teng   +3 more
doaj   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Structure and evolution of the squamate major histocompatibility complex as revealed by two Anolis lizard genomes

open access: yesFrontiers in Genetics, 2022
The major histocompatibility complex (MHC) is an important genomic region for adaptive immunity and has long been studied in ecological and evolutionary contexts, such as disease resistance and mate and kin selection.
Daren C. Card   +8 more
doaj   +1 more source

Biophysical approaches for studying viral entry

open access: yesFEBS Letters, EarlyView.
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley   +1 more source

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

The pyruvate generator is a common phenomenon in mitochondria from different rat and mouse brain regions

open access: yesFEBS Letters, EarlyView.
The pyruvate generator, which causes activation of respiration by extra‐mitochondrial Ca2+, is also present and functional in rat brainstem mitochondria, as it is in other brain regions. This finding is confirmed by experiments with a fully reconstituted malate–aspartate shuttle (MAS).
Grazyna Debska‐Vielhaber   +7 more
wiley   +1 more source

The interaction of resource use and gene flow on the phenotypic divergence of benthic and pelagic morphs of Icelandic Arctic charr (Salvelinus alpinus)

open access: yesEcology and Evolution, 2021
Conceptual models of adaptive divergence and ecological speciation in sympatry predict differential resource use, phenotype–environment correlations, and reduced gene flow among diverging phenotypes.
Matthew K. Brachmann   +3 more
doaj   +1 more source

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