Results 51 to 60 of about 4,039,102 (286)
Ecology and Evolution, 2021 Conceptual models of adaptive divergence and ecological speciation in sympatry predict differential resource use, phenotype–environment correlations, and reduced gene flow among diverging phenotypes.
Matthew K. Brachmann +3 more
doaj +1 more source
Frontiers in Microbiology, 2023 The Usutu virus (USUV) is an emerging arbovirus virus maintained in the environment of Afro-Eurasia via a bird-mosquito-bird enzootic cycle and sporadically infected other vertebrates.
Jianglin Zhou +3 more
doaj +1 more source
Natural Selection: A Deselection vs Proselection Analysis [PDF]
, 2008 Since the dawn of Darwinian evolution theory evolutionists have assumed that evolution favors adaptive traits. In this analysis article the author explores the usefulness of assuming that natural selection works only by disfavoring deleterious ...
Raymond Hardy
core +1 more source
AAA+ protein unfoldases—the Moirai of the proteome
FEBS Letters, EarlyView.AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Natural Induction: Spontaneous Adaptive Organisation without Natural Selection
EntropyEvolution by natural selection is believed to be the only possible source of spontaneous adaptive organisation in the natural world. This places strict limits on the kinds of systems that can exhibit adaptation spontaneously, i.e., without design ...
Christopher L. Buckley +5 more
doaj +1 more source
Evolution of time preference by natural selection [PDF]
, 2009 We reexamine Rogers’ (1994) analysis of the biological basis of the rate of time preference. Although his basic insight concerning the derivation of the felicity function holds up, the functional form he uses does not generate the evolutionary ...
Robson, A., Szentes, B.
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Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
MAHONIA AQUIFOLIUM AS A PROMISING RAW MATERIAL FOR THE FOOD INDUSTRY
Scientific Study & Research: Chemistry & Chemical Engineering, Biotechnology, Food Industry, 2017 The development of the food industry leads to the expansion of the range of processed raw materials. Mahonia aquifolium today can be attributed to the non-traditional agricultural plants.
VLADIMIR N. SOROKOPUDOV +2 more
doaj
Evidence for somatic selection of natural autoantibodies. [PDF]
, 1992 Natural autoantibodies are primarily immunoglobulin M (IgM) antibodies that bind to a variety of self-antigens, including self-IgG. Accounting for a large proportion of the early B cell repertoire, such polyspecific autoantibodies are speculated to ...
Carson, DA +3 more
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