Microbial transformations of natural antitumor agents: oxidation of lapachol by Penicillium notatum [PDF]
, 1978 S L Otten, John P. N. Rosazza
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Comparative study of adenosine 3′‐pyrophosphokinase domains of MuF polymorphic toxins
FEBS Open Bio, EarlyView.With the ultimate goal of understanding the association of toxin‐immunity modules to temperate phages, we characterized toxins from three prophages and examined cross‐protection from immunity proteins. The toxins exhibit adenosine 3′‐pyrophosphokinase activity and are toxic in Escherichia coli.
Eloïse M. Paulet +6 more
wiley +1 more source
Novel Flp pilus biogenesis-dependent natural transformation
Frontiers in Microbiology, 2015 Natural transformation has been described in bacterial species spread through nearly all major taxonomic groups. However, the current understanding of the structural components and the regulation of competence development is derived from only a few model
Angel eAngelov +8 more
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Statistical learning of rational wavelet transform for natural images [PDF]
arXiv, 2017 Motivated with the concept of transform learning and the utility of rational wavelet transform in audio and speech processing, this paper proposes Rational Wavelet Transform Learning in Statistical sense (RWLS) for natural images. The proposed RWLS design is carried out via lifting framework and is shown to have a closed form solution.
arxiv
Microbial transformations of natural antitumor agents: conversion of lapachol to dehydro-alpha-lapachone by Curvularia lunata [PDF]
, 1979 S L Otten, John P. N. Rosazza
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FEBS Open Bio, EarlyView.Ca2+‐mediated response to DMSO was investigated in Saccharomyces cerevisiae cells expressing Ca2+‐dependent aequorin. Cell exposure to DMSO induced a cytosolic Ca2+ wave dependent on the integrity of the Cch1/Mid1 channel. Deletion of KCS1 or VIP1 genes encoding the phosphoinositol pyrophosphate (PP‐IP) synthases suppressed the DMSO‐induced Ca2 ...
Larisa Ioana Gogianu +4 more
wiley +1 more source
Microorganisms, 2016 Horizontal gene transfer (HGT) is a driving force to the evolution of bacteria. The fast emergence of antimicrobial resistance reflects the ability of genetic adaptation of pathogens.
Gabriela Jorge Da Silva, Sara Domingues
doaj +1 more source
Understanding and Overcoming Immunotherapy Resistance in Skin Cancer: Mechanisms and Strategies
Aging and Cancer, EarlyView.This narrative review explores the mechanisms driving immunotherapy resistance in skin cancer, including tumor microenvironment factors, genetic mutations, and immune evasion strategies. It highlights potential strategies to overcome resistance, offering insights for improving therapeutic outcomes and guiding future research in personalized ...
Shreya Singh Beniwal +8 more
wiley +1 more source
On a set of transformations of Gaussian random functions [PDF]
arXiv, 2008 We consider a set of one-dimensional transformations of Gaussian random functions. Under natural assumptions we obtain a connection between $L_2$-small ball asymptotics of the transformed function and of the original one. Also the explicit Karhunen -- Lo\'eve expansion is obtained for a proper class of Gaussian processes.
arxiv
Microbial transformations of natural antitumor agents: use of solubilizing agents to improve yields of hydroxylated ellipticines [PDF]
, 1980 Millie M. Chien, John P. N. Rosazza
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