Results 91 to 100 of about 98,175 (244)

Application of artificial neural network for natural ventilation schemes to control operable windows. [PDF]

Heliyon, 2022
Srisamranrungruang T, Hiyama K.
europepmc   +1 more source

Multimodal AI‐Driven Identification of Dehydrocostus Lactone as a Potent Renal Fibrosis Attenuator Targeting IQGAP1

Advanced Science, EarlyView.
Renal fibrosis, a hallmark of CKD, lacks effective treatments. Herein, we developed a multimodal AI model (TCM‐SPred) to identify anti‐fibrotic agents and found that dehydrocostus lactone (DCL) targets IQGAP1 to inhibit Wnt signaling, blocking the interaction between IQGAP1 and CCT3, demonstrating potent anti‐fibrotic activity in vitro and in vivo ...
Weijiang Lin, Wenzhuo Xu, Kang Liu, Ping Wang, Zhenzhen Zhu, Wenyu Lu, Zhe Zheng, Xiaoqian Peng, Xunkai Yin, Shulan Mei, An Pan, Jian Liu, Lihong Hu   +12 more
wiley   +1 more source

Effect of resilient architecture in an ancient windmill in the Sistan region on natural ventilation enhancement. [PDF]

Sci Rep, 2022
Mohammadi E, Jarkeh M, Zolfaghari SA, Arbabi V.   +3 more
europepmc   +1 more source

Remote Activation of Spinal TRPV1 by Magnetic Nanocubes Confers Cardioprotection Against Myocardial Ischemia‐Reperfusion Injury

Advanced Science, EarlyView.
Fe‐based magnetic nanocubes conjugated with TRPV1 antibodies (FeNCs‐TRPV1) are developed for the specific targeting of TRPV1 channels. Intraspinally injected FeNCs‐TRPV1 induces TRPV1 desensitization in rats exposed to repetitive and transient ACMF.
Xueying Cheng, Shuangyu Liu, Yu Zhang, Kang Peng, Muge Qile, Chao Wu, Mengyun Dou, Liu Liu, Na Yang, Rui Liu, Guiyang Zhang, Liangping Ni, Gaolin Liang, Fang Yang, Ye Zhang, Shufang He   +15 more
wiley   +1 more source

Study of a novel front-roof-back natural ventilation system for Chinese solar greenhouses. [PDF]

R Soc Open Sci, 2022
Zhang L, Liu X, Shi W, Li T, Ji J.
europepmc   +1 more source

TRIM40 Drives Pathological Cardiac Hypertrophy and Heart Failure via Ubiquitination of PKN2

Advanced Science, EarlyView.
This study identifies the E3 ligase TRIM40 as a key driver of pathological cardiac hypertrophy. TRIM40 binds PKN2 via its B‐box domain and, through its C29‐dependent catalytic activity, mediates K63‐linked ubiquitination of PKN2. This modification enhances PKN2 phosphorylation at Ser815, thereby driving hypertrophy.
Risheng Zhao, Xiaoli Cui, Huizhu Du, Zhuoqun Wang, Chang Liu, Linxin Zhang, Jianing Qi, Di Yang, Hui Yu, Shuang Yan, Wei Liu, Haiming Sun, Mengyang Wang   +12 more
wiley   +1 more source

Effects of Radiant Floor Heating Integrated with Natural Ventilation on Flow and Dispersion in a Newly Decorated Residence. [PDF]

Int J Environ Res Public Health, 2022
Cui PY, Wang JQ, Yang F, Zhao QX, Huang YD, Yang Y, Tao WQ.   +6 more
europepmc   +1 more source

Analysis of Multiscale Condensation Phenomena Using a Zero‐Shot Computer Vision Framework

Advanced Science, EarlyView.
A zero‐shot computer vision framework quantifies multiscale condensation dynamics by automatically segmenting droplets and extracting physical parameters without labeled data. The workflow integrates data mining and statistical analysis to reveal droplet growth, coalescence statistics, and sweeping behaviors, enabling label‐free measurement of heat ...
Donghyeong Lee, Seokwan Roh, Jaewoo Jeong, Kuk‐Jin Yoon, Jungchul Lee, Youngsuk Nam   +5 more
wiley   +1 more source

Identification of source location in a single-sided building with natural ventilation: Case of interunit pollutant dispersion. [PDF]

J Build Eng, 2023
Dai Y, Zhang F, Wang H.
europepmc   +1 more source

Study on the Smoke Flow Characteristics in Inclined Tunnel with an Upstream Shaft Under Natural Ventilation

, 2023
Chaopeng Sun, Miaocheng Weng, Fang Liu, Kaiwen Ling   +3 more
openalex   +1 more source