Results 141 to 150 of about 699,210 (251)

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

From perception to modelling: Nature-based solutions as a tool for coastal risk management. [PDF]

Camb Prism Coast Futur
d'Avdeew M, Janin L, Goeldner-Gianella L, Sigwald R, Levasseur A, Lecroart J.   +5 more
europepmc   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Global synthesis and regional insights for mainstreaming urban nature-based solutions. [PDF]

Proc Natl Acad Sci U S A
McPhearson T, Frantzeskaki N, Ossola A, Diep L, Anderson PML, Blatch T, Collier MJ, Cook EM, Culwick Fatti C, Grabowski ZJ, Grimm NB, Haase D, Herreros-Cantis P, Kavonic J, Lin BB, Lopez Meneses DH, Matsler AM, Moglia M, Morató J, O'Farrell P, Roy P, Singh C, Wang J, Zhou W.   +23 more
europepmc   +1 more source

Correction to: Potential of seagrass habitat restorations as nature-based solutions: Practical and scientific implications in Indonesia. [PDF]

Ambio, 2023
Rifai H, Quevedo JMD, Lukman KM, Sondak CFA, Risandi J, Hernawan UE, Uchiyama Y, Ambo-Rappe R, Kohsaka R.   +8 more
europepmc   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Digital fabrication of Hybrid Nature-based Solutions as new opportunity for coastal climate change adaptation. [PDF]

Camb Prism Coast Futur
David CG, Kremer J, Ashwini M, Kloft H, Goseberg N.   +4 more
europepmc   +1 more source

Opportunities for Nature-based Solutions to contribute to Climate-Resilient Development Pathways. [PDF]

Curr Opin Environ Sustain, 2023
Kinol AD, Arango-Quiroga J, Kuhl L.
europepmc   +1 more source

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

FEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong, Yuhei Hosokawa, Lars Oliver Essen, Manuel Maestre‐Reyna   +3 more
wiley   +1 more source

Rethinking trade-offs in nature-based solutions from a multispecies justice perspective. [PDF]

NPJ Urban Sustain
Wijsman K, Pineda-Pinto M, Sarkki S, Stijnen C, den Dekker-Arlain J, Raymond CM.   +5 more
europepmc   +1 more source