Results 121 to 130 of about 1,350,046 (300)

Innovating nature-based solutions: learnings from the EU Horizon 2020 RECONECT project

This paper proposes a specialised framework that integrates the Technology Readiness Levels (TRLs) and the Commercial Readiness Index (CRI) to assess learnings from a Horizon 2020 (H2020) project on innovation development via the selection and ...
Dlugoborskyte, Vytaute, Draper, Kate, Vojinovic, Zoran, Chen, Albert S., Baker, Kate, Penny, Jessica, Fonseca, Alvaro, Manojlovic, Natasa   +7 more
core   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Association between bat-predator species richness and Nipah virus spillover risk in Bangladesh

One Health
Species biodiversity is considered to reduce infectious diseases spillover from wildlife to human. However, despite the potential role of predator biodiversity in this process through trophic cascade, few studies have addressed this issue. In this study,
Jun-Sik Lim, Kyung-Duk Min
doaj   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Nature-Positive Solutions and CGIAR: A pop up exhibit

Nature-Positive Solutions and CGIAR is a pop-up art exhibition featuring information artworks produced in collaboration with The Lexicon of Sustainability and the CGIAR Nature-Positive Solutions Initiative.
CGIAR Nature-Positive Solutions Initiative, Lexicon of Sustainability   +1 more
core  

Enhancing energy sustainability of building projects through nature-based solutions: A fuzzy-based decision support system

Statement of the Problem. Lack of an artificial intelligence (AI)-driven approach to optimize the application of nature-based solutions (NbS) for enhancing energy sustainability in building projects.
Negri, Rogério Galante [UNESP], Felipe Hashimoto Fengler, Rogério Galante Negri, Urban, Rodrigo Custodio [UNESP], Adriano Bressane, Bressane, Adriano [UNESP], Rodrigo Custodio Urban, Liliam César de Castro Medeiros, Fengler, Felipe Hashimoto, Medeiros, Liliam César de Castro [UNESP]   +9 more
core   +1 more source

ESR1 methylation and ESR1 mutations in circulating tumor cells (CTCs) and paired plasma‐cfDNA of advanced breast cancer patients: A feasibility proof‐of‐concept study

Molecular Oncology, EarlyView.
Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou, Athina Markou, Eleonora Nicolo, Mara S Serafini, Qiang Zhang, Youbin Zhang, Lorenzo Gerratana, Andrew A. Davis, Huiping Liu, William J Gradishar, Carolina Reduzzi, Massimo Cristofanilli, Evi Lianidou   +12 more
wiley   +1 more source

Integrating connectivity into actionable spatial planning for nature recovery: Lessons learnt from mapping the Nature Recovery Network in England

Ecological Solutions and Evidence
In England, ecological connectivity is at the core of the ambitious Nature Recovery Network (NRN), a national effort to establish a resilient network of biodiverse places across the country.
Angela Liu, Ben Siggery, Robbie Still, Alison Smith   +3 more
doaj   +1 more source

Variations in the temperature response of photosynthesis among nine common tree species planted in Singapore

Frontiers in Forests and Global Change
Tree planting is regarded as one of the most cost-effective ways to mitigate climate change impacts. As part of the global tree planting movement, the tropical city-state of Singapore initiated a project to plant one million trees in 10 years.
Li Ming Rachel Teo, Liyao Yu, Xiangzhong Luo, Xiangzhong Luo   +3 more
doaj   +1 more source

Smart City with Nature-based Solutions

Establishing nature-based solutions for the development of sustainable and healthy cities: the CLEARING HOUSE project . Nature-based solutions (NBS) are increasingly applied to guide the design of resilient landscapes and cities to enable them to reach ...
Raffaele Lafortezza
core