Results 41 to 50 of about 439,678 (306)

Innovative Teaching Systems in Teaching about Nature and Society at the Level of Initial Education

open access: yesDruštvene i humanističke studije (Online), 2023
In contrast to classical teaching, innovative teaching about nature and society is based on innovative teaching systems and innovative didactic-methodical systems by which teaching is planned, implemented, and evaluated in reverse design. The goal of this conducted research is to identify teachers' assessments of their familiarity with innovative ...
Hadži Živorad Milenović   +1 more
openaire   +2 more sources

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

ECONOMIC PREREQUISITES FOR THE DEVELOPMENT OF THE ECOLOGICAL CULTURE OF FUTURE TRANSPORT PROFESSIONALS

open access: yesФінансово-кредитна діяльність: проблеми теорії та практики, 2021
. The aim of the article is to study the economic prerequisites for the development of ecological culture of future transport professionals and analyze foreign experience of ecological education of students to adapt their best practices to Ukrainian ...
M. Klymenko   +3 more
doaj   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

The Nature of Conversation of Primary Students in Technology Education: Implications for Teaching and Learning

open access: yes, 2013
Classroom conversations are core to establishing successful learning for students. This research explored the nature of conversation in technology education in the primary classroom and the implications for teaching and learning.
Fox-Turnbull, Wendy Helen
core   +1 more source

Adventure Playground as an Example of the Child’s Right to Play [PDF]

open access: yesПсихологическая наука и образование (2007. Online), 2014
We analyze the history of creation, structure and psychological foundations of adventure playgrounds, which appeared and became widespread in Europe during the second half of the XX century. Adventure playground is an example of realization of children’s
Kotlyar (Korepanova) I.A.   +1 more
doaj  

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Aktualisasi Pendidikan Fikih Lingkungan (Fiqh Al-Bi’ah) pada Masyarakat Kawasan Hutan Desa Genggelang Kecamatan Gangga Kab. Lombok Utara

open access: yesManazhim, 2023
Nature or the environment cannot be separated from the social life of society. The actualization of environmental fiqh education (fiqh al-bi'ah) in society is considered capable of minimizing problems in forest area environmental cases.
Sujono Indrajati   +2 more
doaj   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

open access: yesMolecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute   +4 more
wiley   +1 more source

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