Results 61 to 70 of about 3,062,276 (306)
FEBS Open Bio, EarlyView.Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source
Real‐World Performance of CSF Kappa Free Light Chains in the 2024 McDonald Criteria
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Kappa free light chains (KFLCs) in the cerebrospinal fluid (CSF) have a similar performance to CSF‐restricted oligoclonal bands (OCB) for multiple sclerosis (MS) diagnosis. To help with implementation, we set out to resolve several remaining uncertainties: (1) performance in a real‐world cohort and the 2024 McDonald criteria; (2 ...
Maya M. Leibowitz +11 more
wiley +1 more source
The education system in Indonesia at a time of significant changes
Revue Internationale d’Éducation de Sèvres, 2014 Indonesia’s national education system developed from the struggle for independence and the renaissance of the nation. During its development, many influences, local or global, contributed to the changing nature of the curriculum, pedagogy, assessment ...
Tatang Suratno
doaj +1 more source
A Review of Work Based Learning in Higher Education [PDF]
, 1996 The idea of work based learning in higher education might sound like a contradiction in terms. Work based learning is surely in the the workplace. The senses in which it might also, under certain conditions, be in higher education are explored in this ...
Brennan, John, Little, Brenda
core
Remote Assessment of Ataxia Severity in SCA3 Across Multiple Centers and Time Points
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Spinocerebellar ataxia type 3 (SCA3) is a genetically defined ataxia. The Scale for Assessment and Rating of Ataxia (SARA) is a clinician‐reported outcome that measures ataxia severity at a single time point. In its standard application, SARA fails to capture short‐term fluctuations, limiting its sensitivity in trials.
Marcus Grobe‐Einsler +20 more
wiley +1 more source
EDUCATION IN SEARCH OF THE ADEQUACY PRINCIPLE
Образование и наука, 2015 The paper discusses the acute methodology problem: elicitation of the fundamental principle of modern education. In the course of retrospective analysis, the author attempts to trace the essence and comparative historical specificity of the principle in ...
Y. V. Larin
doaj +1 more source
Clustering Algorithm Reveals Dopamine‐Motor Mismatch in Cognitively Preserved Parkinson's Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To explore the relationship between dopaminergic denervation and motor impairment in two de novo Parkinson's disease (PD) cohorts. Methods n = 249 PD patients from Parkinson's Progression Markers Initiative (PPMI) and n = 84 from an external clinical cohort.
Rachele Malito +14 more
wiley +1 more source
Экологическая культура на предприятиях строительных материалов [PDF]
, 2014 Formation of the ecological culture including understanding and use in activity of the person and society of values, uniting in a whole the nature, culture and society in their interrelation and interdependence, — is the most important problem of ...
Русан, А.
core
The Optimal Subsidies to Higher Education, with Reference to Education and Research [PDF]
, 2005 We consider a society which consists of two sectors, the educational sector and the production sector. We define the educational sector as one that produces two outputs jointly, higher education forming human capital and research increasing the stock of ...
Furumatsu, Noriko, Shirai, Masatoshi
core +1 more source
Impact of Asymptomatic Intracranial Hemorrhage on Outcome After Endovascular Stroke Treatment
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Endovascular treatment (EVT) achieves high rates of recanalization in acute large‐vessel occlusion (LVO) stroke, but functional recovery remains heterogeneous. While symptomatic intracranial hemorrhage (sICH) has been well studied, the prognostic impact of asymptomatic intracranial hemorrhage (aICH) after EVT is less certain ...
Shihai Yang +22 more
wiley +1 more source