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Potential Interactions of Drug–Natural Health Products and Natural Health Products–Natural Health Products among Children

The Journal of Pediatrics, 2008
To determine the frequency of concurrent use of conventional medications and natural health products (NHP) and their potential interactions in children arriving at an emergency department.A survey of parents and patients 0 to 18 years at a large pediatric ED in Toronto, Ontario, Canada.A total of 1804 families were interviewed in this study. Concurrent
Ran D, Goldman   +3 more
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Simple “On‐Demand” Production of Bioactive Natural Products

ChemBioChem, 2015
AbstractExchange of the native promoter to the arabinose‐inducible promoter PBAD was established in entomopathogenic bacteria to silence and/or activate gene clusters involved in natural product biosynthesis. This allowed the “on‐demand” production of GameXPeptides, xenoamicins, and the blue pigment indigoidine.
Bode, Edna   +8 more
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DNA Encoding of Natural Products

2022
DNA-encoded library (DEL) links the powers of genetics and chemicals via high-efficient enzymatic ligation of DNA barcodes and the "split and pool" combinatorial synthesis. Natural products (NPs) are evolutionary optimized compounds that have played a key role in the history of human drug discovery.
Hongtao, Xu, Peixiang, Ma
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Structural Simplification of Natural Products

Chemical Reviews, 2019
Natural products (NPs) are important sources of clinical drugs due to their structural diversity and biological prevalidation. However, the structural complexity of NPs leads to synthetic difficulties, unfavorable pharmacokinetic profiles, and poor drug-likeness.
Shengzheng Wang   +2 more
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Toxicology of natural products

Food and Cosmetics Toxicology, 1965
Summary The difficulties are discussed of correlating chronic ‘diseases’, especially those encountered in the tropics and subtropics, with the ingestion of natural toxic materials, whether of plant, microbial or animal origin. Chronic conditions, such as tumours, goitres, embryopathies, haematological and neurological disorders might possibly be ...
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Combinatorial synthesis of natural products

Current Opinion in Chemical Biology, 2002
AbstractFor Abstract see ChemInform Abstract in Full Text.
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Antiplatelet properties of natural products

Vascular Pharmacology, 2013
Cardiovascular diseases (CVD) and its main underlying cause, atherothrombosis, are the major culprits of morbidity and mortality worldwide. Apart from the treatment of cardiovascular risk factors and the use of antithrombotic agents there is considerable interest in the role of natural food products and their bioactive components in the prevention and ...
Gemma, Vilahur, Lina, Badimon
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Countercurrent Separation of Natural Products

Journal of Natural Products, 2008
An assessment of the technology and method development in countercurrent chromatography (CCC) and centrifugal partition chromatography (CPC), collectively referred to as countercurrent separation (CS), is provided. More than six decades of CS theory and applications are critically reviewed and developed into a practical guide to CS for natural products
Guido F, Pauli   +2 more
openaire   +2 more sources

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