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Natural and engineered biosynthesis of fluorinated natural products
Chem. Soc. Rev., 2014Studying the biosynthesis of naturally-occurring and engineered organofluorine natural products may enable the development of new bioactive small molecules.
Mark C, Walker, Michelle C Y, Chang
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Isolation of Marine Natural Products
2006Marine macro- and micro-biota offer a wealth of chemically diverse compounds that have been evolutionary preselected to modulate biochemical pathways. Many industrial and academic groups are accessing this source using advanced technology platforms. The previous edition of this chapter offered some practical guidance in the process of extraction and ...
Wael E, Houssen, Marcel, Jaspars
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Microbial production of natural raspberry ketone
Biotechnology Journal, 2007AbstractRaspberry ketone is an important compound for the flavour industry. It is frequently used in products such as soft drinks, sweets, puddings and ice creams. The compound can be produced by organic synthesis. Demand for “natural” raspberry ketone is growing considerably. However, this product is extremely expensive.
Beekwilder, M.J. +6 more
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Biocatalytic modification of natural products
Current Opinion in Chemical Biology, 2001Natural products are ideal training compounds for enzymatic catalysis. New transformations have become possible on a preparative scale thanks to molecular biology, which has made many new enzymes available. Additionally, new synthetic pathways have been developed to regenerate expensive cofactors in situ and to improve enzyme selectivity.
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Isolation of Microbial Natural Products
2012In principle, the isolation of secondary metabolites from microbes does not differ from their isolation from other organisms. The extraction procedure may of course be quite different, especially if it is carried out in an industrial scale, but when an extract containing the metabolites of interest is at hand, it is the same palette of adsorbents and ...
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Combinatorial Biosynthesis of Natural Products
Journal of Medicinal Chemistry, 2008Wenjun, Zhang, Yi, Tang
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Revitalizing the production of nature thesis
Progress in Human Geography, 2013Michael Ekers, Alexander John Loftus
exaly