Results 71 to 80 of about 181,914,409 (290)
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Assessing epistemological beliefs of experts and novices via practices in authentic science inquiry
International Journal of STEM Education, 2019 Background Achieving science literacy requires learning disciplinary knowledge, science practices, and development of sophisticated epistemological beliefs about the nature of science and science knowledge.
Melanie E. Peffer, Niloofar Ramezani
doaj +1 more source
Proceedings of the Arizona-Nevada Academy of Science, Volume 20 (1985)
, 1985 TWENTY NINTH ANNUAL MEETING / April 27, 1985 / Joint Meeting with the Pacific Division of the American Association for the Advancement of Science / Participating Societies: Arizona Junior Academy of Science, American Water Resources Association ...
Arizona-Nevada Academy of Science
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Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Measuring Nature of Science Views of Middle School Students
International Journal of Assessment Tools in Education, 2019 Developingscientific literacy for all students is the most often stated purpose ofcontemporary science education. Nature of science (NOS) is seen as an importantcomponent of scientific literacy.
Yalçın Yalaki +5 more
doaj +1 more source
Proceedings of the Arizona-Nevada Academy of Science, Volume 23 (1988)
, 1988 THIRTY-SECOND ANNUAL MEETING / April 16, 1988 / Participating Societies - Arizona Junior Academy of Science, American Water Resources Association, Arizona Hydrological Society / University of Arizona / Tucson, ArizonaThis volume is part of the Arizona ...
Arizona-Nevada Academy of Science
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FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Proceedings of the Arizona-Nevada Academy of Science, Volume 08 (1973)
, 2014 SEVENTEENTH ANNUAL MEETING / May 4-5, 1973 / Participating Societies: Arizona-Nevada Junior Academy of Science, American Water Resources Association / University of Arizona / Tucson, ArizonaThis volume is part of the Arizona-Nevada Academy of Science ...
Arizona-Nevada Academy of Science
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FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Proceedings of the Arizona-Nevada Academy of Science, Volume 01 (1960)
, 1960 FIRST ANNUAL MEETING / April 9, 1960 / Arizona-Sonora Desert Museum and University of Arizona / Tucson, ArizonaThis volume is part of the Arizona-Nevada Academy of Science collections.
Arizona-Nevada Academy of Science
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