Results 141 to 150 of about 493,608 (306)
Development of a nalmefene formulation suitable for a community‐use auto‐injector
British Journal of Clinical Pharmacology, EarlyView.Aim Time to onset of reversal is critical when treating opioid‐induced respiratory depression and hypoxia. This study aimed to develop a formulation of the opioid antagonist nalmefene with an increased absorption rate and reduced time to onset of reversal following intramuscular administration. Methods Several absorption enhancers were screened in rats,
Alessandra Cipriano +6 more
wiley +1 more source
Management of postoperative nausea and vomiting: focus on palonosetron
, 2008 Neil A Muchatuta1, Michael J Paech21Department of Anaesthesia and Pain Medicine, King Edward Memorial Hospital for Women, Perth, Western Australia; 2Pharmacology and Anaesthesiology Unit, The School of Medicine and Pharmacology, The University of Western
Michael J Paech, Neil A Muchatuta
core
British Journal of Clinical Pharmacology, EarlyView.Chronic pain represents a complex debilitating condition that extends beyond the protective function of physiological pain, often persisting as an independent disease entity. Chronic primary and secondary pain syndromes reflect a multifaceted continuum involving nociceptive, neuropathic and nociplastic mechanisms.
Stefania Nobili +6 more
wiley +1 more source
, 2017 Yvonne Jelting,1 Christian Klein,1 Thomas Harlander,1 Leopold Eberhart,2 Norbert Roewer,1 Peter Kranke1 1Department of Anesthesia and Critical Care, University Hospitals of Wuerzburg, Wuerzburg, 2Department of Anesthesiology and Critical Care Medicine ...
Roewer N +5 more
core
British Journal of Clinical Pharmacology, EarlyView.Aims This work aimed to evaluate the efficacy and safety of cannabinoids for the treatment of MS‐related spasticity. Methods Systematic searches were conducted in PubMed, EMBASE, and LILACS on 2 December 2025. Randomized controlled trials evaluating natural or synthetic cannabinoids for MS‐related spasticity were included.
Letícia Hamm‐Buiar +3 more
wiley +1 more source
Optimal management of nausea and vomiting of pregnancy
, 2010 Neda Ebrahimi1,2, Caroline Maltepe2, Adrienne Einarson21Pharmaceutical Sciences, University of Toronto, Toronto, Ontario, Canada; 2Motherisk Program, The Hospital for Sick Children, Toronto, Ontario, CanadaAbstract: Nausea and vomiting of pregnancy (NVP)
Adrienne Einarson +2 more
core
British Journal of Clinical Pharmacology, EarlyView.Aims Information on the safety profile of antidiabetic medications is essential for informed treatment decisions in type 2 diabetes mellitus. Although this information is available in regulatory documents of individual drugs, a comprehensive overview across all approved antidiabetics is lacking.
David Liang +5 more
wiley +1 more source
Comparison of Recovery Time of Anesthesia And Complication After The Use Of Alfentanil And Remifentanil In Cataract Surgery Of Elderly [PDF]
Background & Objective: With consideration the daily increased development of outpatient surgeries and high rate of these operations in elderly patients, rapid and safe recovery of patients for coming back to daily life is necessary.
اخوان اکبری, قدرت +2 more
core
An ETH‐LAD trip with unfavourable consequences: A case report
British Journal of Clinical Pharmacology, EarlyView.Numerous analogues of the psychedelic and internationally controlled hallucinogen LSD have been described; however, only a limited number have been systematically investigated. This report presents the first case with an analytically confirmed ingestion of ETH‐LAD (6‐ethyl‐6‐nor‐lysergic acid diethylamide), the N‐ethyl derivative of LSD.
Johannes Nadler +6 more
wiley +1 more source