Results 141 to 150 of about 506,258 (301)
British Journal of Clinical Pharmacology, EarlyView.. Aims Traditional pharmacovigilance detects single drug–event associations but cannot readily characterize multi‐system adverse‐event patterns such as fluoroquinolone‐associated disability. We evaluated unsupervised machine learning for this purpose, using fluoroquinolones as an exemplar.
Niaz Chalabianloo +3 more
wiley +1 more source
British Journal of Clinical Pharmacology, EarlyView.Abstract Background We conducted a systematic review of clinical trials and cohort studies on HIV post‐exposure prophylaxis (PEP) regimens to inform updated 2025 Canadian guidelines. Methods We searched Medline and Embase (July 2017–June 2024) for studies reporting on: HIV acquisition, PEP completion, adverse events (AEs) leading to discontinuation and/
Stanley O. Onyegbule +12 more
wiley +1 more source
Nausea and Vomiting Management Barriers Questionnaire Dataset
Observational, descriptive study of patient perceptions of chemotherapy related nausea and vomiting. The patient sample consists of N=299 who completed socio-demographic and clinical items as well as a Nausea and Vomiting Management Barriers ...
Cella, Dave
core +1 more source
British Journal of Clinical Pharmacology, EarlyView.Aims Enavogliflozin, a sodium‐glucose cotransporter 2 inhibitor, is expected to be coadministered with antihyperglycaemic drugs with different mechanisms of action. This study aimed to investigate the pharmacokinetic (PK) and pharmacodynamic (PD) interactions between enavogliflozin, glimepiride and metformin.
Kyungrin Chang +5 more
wiley +1 more source
British Educational Research Journal, EarlyView.Abstract School Attendance Problems (SAPs) represent a significant challenge requiring early identification and intervention. Current service provision often does not recognise early indicators that parents observe, creating gaps between when initial concerns are raised and formal support is provided.
Tereza Aidonopoulou‐Read +4 more
wiley +1 more source
Chiari I Malformation: Review and Update of Current Treatment Options
Clinical Anatomy, EarlyView.ABSTRACT The pathophysiology of Chiari malformation type I (CM‐I) is complex, involving structural abnormalities at the craniovertebral junction that result in herniation of the cerebellar tonsils through the foramen magnum. In this study, we aim to present and evaluate current treatment options for CM‐I, with a focus on evidence‐based clinical ...
Jordan J. Lo +11 more
wiley +1 more source
Using Anatomy to Prepare Healthcare Students for Patient Death: A Systematic Review
Clinical Anatomy, EarlyView.ABSTRACT Healthcare students frequently encounter death in clinical practice, yet formal curricula may not appropriately prepare them for its emotional and ethical challenges. Anatomy education using human body donors has the potential to provide early, structured exposure to death, potentially shaping professional, cognitive, and emotional ...
Lucy C. Cowperthwaite +2 more
wiley +1 more source
Contemporary management of pain in cirrhosis: Toward precision therapy for pain
Hepatology, EarlyView., 2022 Abstract Chronic pain is highly prevalent in patients with cirrhosis and is associated with poor health‐related quality of life and poor functional status. However, there is limited guidance on appropriate pain management in this population, and pharmacologic treatment can be harmful, leading to adverse outcomes, such as gastrointestinal bleeding ...
Alexis Holman +4 more
wiley +1 more source