Ca2+ entry through NaV channels generates submillisecond axonal Ca2+ signaling
eLife, 2020 Calcium ions (Ca2+) are essential for many cellular signaling mechanisms and enter the cytosol mostly through voltage-gated calcium channels. Here, using high-speed Ca2+ imaging up to 20 kHz in the rat layer five pyramidal neuron axon we found that ...
Naomi AK Hanemaaijer +5 more
doaj +2 more sources
LM-Nav: Robotic Navigation with Large Pre-Trained Models of Language, Vision, and Action [PDF]
Conference on Robot Learning, 2022 Goal-conditioned policies for robotic navigation can be trained on large, unannotated datasets, providing for good generalization to real-world settings.
Dhruv Shah +3 more
semanticscholar +1 more source
GA-Nav: Efficient Terrain Segmentation for Robot Navigation in Unstructured Outdoor Environments [PDF]
IEEE Robotics and Automation Letters, 2021 We propose GA-Nav, a novel group-wise attention mechanism to identify safe and navigable regions in unstructured environments from RGB images. Our group-wise attention method extracts multi-scale features from each type of terrain independently and ...
Tianrui Guan +5 more
semanticscholar +1 more source
Nav-Q: quantum deep reinforcement learning for collision-free navigation of self-driving cars [PDF]
Quantum Machine Intelligence, 2023 The task of collision-free navigation (CFN) of self-driving cars is an NP-hard problem usually tackled using deep reinforcement learning (DRL). While DRL methods have proven to be effective, their implementation requires substantial computing resources ...
Akash Sinha +2 more
semanticscholar +1 more source
CLIP-Nav: Using CLIP for Zero-Shot Vision-and-Language Navigation [PDF]
arXiv.org, 2022 Household environments are visually diverse. Embodied agents performing Vision-and-Language Navigation (VLN) in the wild must be able to handle this diversity, while also following arbitrary language instructions.
Vishnu Sashank Dorbala +4 more
semanticscholar +1 more source
Cannabidiol inhibits Nav channels through two distinct binding sites
Nature Communications, 2023 Cannabidiol (CBD), a major non-psychoactive phytocannabinoid in cannabis, is an effective treatment for some forms of epilepsy and pain. At high concentrations, CBD interacts with a huge variety of proteins, but which targets are most relevant for ...
Jian Huang +7 more
semanticscholar +1 more source
A structural atlas of druggable sites on Nav channels
Channels, 2023 Voltage-gated sodium (Nav) channels govern membrane excitability by initiating and propagating action potentials. Consistent with their physiological significance, dysfunction, or mutations in these channels are associated with various channelopathies ...
Zhangqiang Li, Qiurong Wu, Nieng Yan
semanticscholar +1 more source
The financial performance of selected REITs from S&P500 [PDF]
Anali Ekonomskog fakulteta u Subotici, 2023 Every investor, trader, portfolio manager or analyst tries to evaluate the performance of the selected asset to develop a strategy for investment or trading. There are a variety of analyses that can be used depending on the asset class chosen. Since this
Cicmil Danica
doaj
Dual-pocket inhibition of Nav channels by the antiepileptic drug lamotrigine
Proceedings of the National Academy of Sciences of the United States of America, 2023 Significance Dissecting the mechanism of action of clinical drugs on human Nav channels will aid future drug discovery for the treatment of neurological and psychiatric disorders.
Jian Huang +4 more
semanticscholar +1 more source
Information Distribution in Multi-Robot Systems: Utility-Based Evaluation Model
Sensors, 2020 This work addresses the problem of information distribution in multi-robot systems, with an emphasis on multi-UAV (unmanned aerial vehicle) applications.
Michał Barciś +2 more
doaj +1 more source