Suzetrigine as a Novel Non-opioid Analgesic Drug in Pain Management: A Review of Clinical Evidence and Therapeutic Perspectives. [PDF]
CureusMach M +4 more
europepmc +1 more source
Targeting Na<sub>v</sub>1.8 with the nonopioid antagonist suzetrigine for analgesia: cause for optimism? [PDF]
Br J AnaesthAttal N, Barrot M.
europepmc +1 more source
Arthritis pain: moving between early- and late- stage disease [PDF]
, 2017 Ashraf +9 more
core +2 more sources
Piezo1-mediated neuroexcitation via collaboration with KCa1.1 and Nav1.9 currents in myelinated Ah-type of trigeminal ganglion neurons in rats: Mechanistic insights with sex-specific effects. [PDF]
Mol PainLiu Y +7 more
europepmc +1 more source
A novel target for analgesic substances: physiological role of Na,K-ATPase as the signal transducer. [PDF]
Front Mol NeurosciPenniyaynen VA +11 more
europepmc +1 more source
Scorpion toxin BmK I directly activates Nav1.8 in primary sensory neurons to induce neuronal hyperexcitability in rats [PDF]
, 2015 Feng Jiang +7 more
core +1 more source
A nociceptor excitability test for identifying alterations of the Nav1.7 channels in humans. [PDF]
PainMørch CD +6 more
europepmc +1 more source
Modulation of human dorsal root ganglion neuron firing by the Nav1.8 inhibitor suzetrigine. [PDF]
Proc Natl Acad Sci U S AStewart RG +6 more
europepmc +1 more source
Loss of Glutaminase 1 in Small Sensory Neurons Prevents Nerve Injury Induced Mechanical Allodynia: Insights From Conditional Knockout Mice. [PDF]
Eur J PainMartínez-Padilla A +4 more
europepmc +1 more source
FDA approves Journavx (Suzetrigine) as the first non-opioid treatment for moderate to severe acute pain. [PDF]
Ann Med Surg (Lond)Aamir MB +5 more
europepmc +1 more source