Results 81 to 90 of about 8,067 (198)

The Role of Neuro‐Immune Regulation in the Pathogenesis of Psoriasis

Journal of Immunology Research, Volume 2026, Issue 1, 2026.
Psoriasis is a chronic inflammatory skin disease characterized by abnormal proliferation of epidermal cells induced by an overactive immune system. In addition to the interaction between immune cells and keratinocytes, emerging research highlights the indispensable role of peripheral sensory neurons in the initiation and progression of psoriatic ...
Xin Liu, Mingyu Yu, Pan Zou, Suwen Liu, Jian Jiang, Liyang Ge, Su Jiang, Jingyu Zhang, Xin Wang, Hongxiang Chen, Poorani Gurumallesh Prabu   +10 more
wiley   +1 more source

Distinct subsets of unmyelinated primary sensory fibers mediate behavioral responses to noxious thermal and mechanical stimuli [PDF]

, 2009
Behavioral responses to painful stimuli require peripheral sensory neurons called nociceptors. Electrophysiological studies show that most C-fiber nociceptors are polymodal (i.e., respond to multiple noxious stimulus modalities, such as mechanical and ...
A. I. Basbaum, Abrahamsen, Barclay, Bautista, Bautista, Binshtok, Cain, Caterina, Caterina, Caterina, Caterina, Caterina, Chandrashekar, D. J. Anderson, D. J. Cavanaugh, Davis, Dong, Fitzgerald, Gamse, H. Lee, Holzer, Julius, Karai, L. Lo, Lawson, Lee, Lewinter, Luquet, M. J. Zylka, MELZACK, Molliver, Perl, Perl, Potrebic, Price, S. D. Shields, Saito, Story, Stucky, Tarpley, Vulchanova, Yaksh   +41 more
core   +4 more sources

Artificial skin sensation for neuroprosthetic hands

FlexMat, Volume 2, Issue 4, Page 458-474, December 2025.
In this review, Li et al. provide a systematic summary of the design strategy and performance of flexible tactile sensors for neuroprosthetic hands, which can efficiently transduce environmental stimuli such as pressure, temperature, and pain. The comparisons of sensing modality between human skin and each flexible sensor subtype are also discussed ...
Yue Li, Tie Li, Ting Zhang, Zheng Liu
wiley   +1 more source

Nav1.8-expressing neurons control daily oscillations of food intake, body weight and gut microbiota in mice

Communications Biology
Recent evidence suggests a role of sensory neurons expressing the sodium channel Nav1.8 on the energy homeostasis control. Using a murine diphtheria toxin ablation strategy and ad libitum and time-restricted feeding regimens of control or high-fat high ...
Clara Bullich-Vilarrubias, Marina Romaní-Pérez, Inmaculada López-Almela, Teresa Rubio, Carlos J. García, Francisco A. Tomás-Barberán, Yolanda Sanz   +6 more
doaj   +1 more source

Characteristics of sensory neuronal groups in CGRP-cre-ER reporter mice: Comparison to Nav1.8-cre, TRPV1-cre and TRPV1-GFP mouse lines. [PDF]

PLoS ONE, 2018
Peptidergic sensory neurons play a critical role in nociceptive pathways. To precisely define the function and plasticity of sensory neurons in detail, new tools such as transgenic mouse models are needed.
Mayur J Patil, Anahit H Hovhannisyan, Armen N Akopian   +2 more
doaj   +1 more source

Shoulder pain due to cervical radiculopathy: an underestimated long-term complication of herpes zoster virus reactivation? [PDF]

, 2018
Purpose To evaluate if herpes zoster virus (HZV) reactivation may be considered in the aetiology of cervical radiculopathy. Methods The study group was composed of 110 patients (52 M-58F;mean age ± SD:46.5 ± 6.12; range:40-73) with a clinical ...
AS Hilibrand, B Kuijper, Ciro Villani, DA Perez-Martienz, Daniele Passaretti, DH Gilden, E Viikari-Juntura, H Sandmark, HC Tong, I Steiner, JP Makela, K Radhakrishnan, KC Shah, KM Abbed, MC Sanchez, MM Ban Le, MM Vargo, MT Modic, MT Modic, NA Peterslund, PG Kennedy, PW Detwiler, R Atkinson, RE Yoss, RS Wainner, RW Johnson, S Gumina, S Shabat, Stefano Gumina, T Fujy, Vittorio Candela, W Frobin, W Frobin, W Frobin, Y Uematsu   +34 more
core   +1 more source

The Concise Guide to PHARMACOLOGY 2025/26: Ion channels

British Journal of Pharmacology, Volume 182, Issue S1, Page S152-S241, December 2025.
The Concise Guide to Pharmacology 2025/26 marks the seventh edition in this series of biennial publications in the British Journal of Pharmacology. Presented in landscape format, the guide provides a comparative overview of the pharmacology of drug target families. The concise nature of the Concise Guide refers to the style of presentation, being clear,
Stephen P. H. Alexander, Jörg Striessnig, Alasdair J. Gibb, Alistair A. Mathie, Emma L. Veale, Eamonn Kelly, Chloe J. Peach, Jane F. Armstrong, Elena Faccenda, Simon D. Harding, Christopher Southan, Jamie A. Davies, Richard W. Aldrich, Bernard Attali, Austin M. Baggetta, Elvir Becirovic, David J. Beech, Martin Biel, Roslyn M. Bill, Ana I. Caceres, William A. Catterall, Han Chow Chua, Alex C. Conner, Henry Danahay, Paul Davies, Katrien De Clerq, Markus Delling, Francesco Di Virgilio, Simonetta Falzoni, Wei Fang, Stefanie Fenske, Anna Fortuny‐Gomez, Samuel Fountain, George K. Chandy, Mohammad‐Reza Ghovanloo, Steve A. N. Goldstein, Martin Gosling, Christian Grimm, Stephan Grissmer, Kotdaji Ha, Tim G. Hales, Verena Hammelmann, Israel Hanukoglu, Meiqin Hu, Ad P. Ijzerman, Sairam V. Jabba, Mike Jarvis, Anders A. Jensen, Sven E. Jordt, Leonard K. Kaczmarek, Stephan Kellenberger, Charles Kennedy, Brian King, Philip Kitchen, Qiang Liu, Joseph W. Lynch, Rian W. Manville, Jessica Meades, Verena Mehlfeld, Annette Nicke, Stefan Offermanns, Edward Pérez‐Reyes, Leigh D. Plant, Stephan A. Pless, Lachlan D. Rash, Dejian Ren, Hussein N. Rubaiy, Mootaz M. Salman, Werner Sieghart, Lucia G. Sivilotti, Trevor G. Smart, Terrance P. Snutch, Paolo Tammaro, Jinbin Tian, James S. Trimmer, Charlotte Van den Eynde, Paola Vergani, Joris Vriens, Stephen G. Waxman, Aguan D. Wei, Brenda T. Winn, Heike Wulff, Haoxing Xu, Fan Yang, Lixia Yue, Xiaoli Zhang, Michael Zhu   +86 more
wiley   +1 more source

Modeling the pore structure of voltage-gated sodium channels in closed, open, and fast-inactivated conformation reveals details of site 1 toxin and local anesthetic binding [PDF]

, 2018
In this work molecular modeling was applied to generate homology models of the pore region of the Na v 1.2 and Na v 1.8 isoforms of human voltage-gated sodium channels.
Blaney, Frank, Clare, Jeff, Dale, Tim, Guex, Nicolas, McLay, Iain, Robertson, Graeme, Scheib, Holger, Tate, Simon   +7 more
core  

Molecular Sensors and Modulators of Thermoreception [PDF]

, 2015
Peer ...
Zhang, Xuming
core   +1 more source

Morpho‐Histo‐Cytological Evaluation of Oral Tissues in Burning Mouth Syndrome: A Systematic Review

Journal of Oral Rehabilitation, Volume 52, Issue 12, Page 2449-2480, December 2025.
This systematic review on Burning Mouth Syndrome (BMS) included 14 studies that examined histological changes. 12 studies used incisional biopsies and 2 used exfoliative cytology. Histology and molecular biology techniques were used to assess morphological, phenotypical and genomic changes in oral tissues, primarily from the tongue.
André Luís Porporatti, Ângela Graciela Deliga Schroder, Ashley Lebel, Nathan Moreau, Annabelle Réaux‐Le Goazigo, Ihsène Taïhi, Heike Rittner, Tara Renton, Yves Boucher   +8 more
wiley   +1 more source