Results 61 to 70 of about 36,134 (309)

The Efficacy of Chaihu-Guizhi-Ganjiang Decoction on Chronic Non-Atrophic Gastritis with Gallbladder Heat and Spleen Cold Syndrome and Its Metabolomic Analysis: An Observational Controlled Before-After Clinical Trial [Response to Letter]

open access: yesDrug Design, Development and Therapy
Tao Wen,1,* Xuan Liu,2,* Tao Pang,1,* Mingming Li,1 Guangyang Jiao,3 Xiangcheng Fan,1 Jigui Tang,4 Ci’an Zhang,4 Zhipeng Wang,1 Xiaoqiang Yue,4,* Wansheng Chen,1,3,5 Feng Zhang1,5 1Department of Pharmacy, Changzheng Hospital, Naval ...
Wen T   +11 more
doaj  

Serum amino acid alterations in hyperuricemia: potential targets for renal disease prevention

open access: yesAmino Acids
Observational studies have linked uric acid (UA) levels and kidney disease to amino acid homeostasis, but the causal relationship is unclear. This study aims to determine if elevated UA affects amino acid levels and whether amino acids mediate this ...
Qinglin Sheng   +11 more
doaj   +1 more source

Artificial Intelligence‐Driven Soft Bioelectronics for Self‐Powered Respiration Monitoring

open access: yesAdvanced Science, EarlyView.
Artificial intelligence‐driven soft bioelectronics for self powered respiration monitoring based on triboelectric nanogenerators (TENGs), piezoelectric nanogenerators (PENGs), and magnetoelastic generators (MEGs) enable continuous and multi‐scenario respiratory biomechanical data collection. Coupled with machine learning and big data driven diagnostics,
Xinkai Xu, Xiao Xiao, Rui Guo, Jun Chen
wiley   +1 more source

Nanocarrier-Mediated Immunogenic Cell Death for Melanoma Treatment

open access: yesInternational Journal of Nanomedicine, 2023
Jiandong Wang,1– 3,* Jinyuan Ma,1,4,* Zongguang Tai,1,4,* Lisha Li,1,4 Tingrui Zhang,1,4 Tingting Cheng,1– 3 Junxia Yu,1– 3 Quangang Zhu,1,4 Leilei Bao,2 Zhongjian Chen1,4 1Shanghai Skin Disease Hospital, School of Medicine, Tongji University,
Wang J   +9 more
doaj  

Immunoaffinity‐Mimetic Assembly of Peptide‐Aptamer Conjugates and Stem Cell‐Derived Exosomes into Hierarchical Microgels for Spinal Cord Injury Repair

open access: yesAdvanced Science, EarlyView.
Inspired by antibody‐antigen binding, this study develops an unprecedented immunoaffinity‐mimetic assembly strategy, with Peptide‐AptCD63 conjugates acting as antibody surrogates binding CD63 epitopes on mesenchymal stem cell‐derived exosomes. This creates a hierarchical microstructure intended to synergistically integrate antioxidative and anti ...
Dantong Zheng   +8 more
wiley   +1 more source

Gelsolin regulates intestinal stem cell regeneration and Th17 cellular function

open access: yesCell Communication and Signaling
Intestinal stem cells (ISCs) are responsible for intestinal homeostasis and are important for the regeneration of damaged intestine. We established an ionizing radiation (IR)-induced intestinal injury model and observed that Gelsolin KO mice had ...
Jicong Du   +12 more
doaj   +1 more source

Enhanced Responsivity, Accuracy, and Stability of Aerosol Jet Printing via Mechanical Switching Valve Assisted Internal Shuttering

open access: yesAdvanced Science, EarlyView.
This work demonstrates ultra‐high ON‐OFF responsivity of AJP by mechanical switching valve assisted shuttering. The jet relaxation and ON‐OFF delay are substantially eliminated from greater than 35 s, maintaining patterning quality independent of the variations of printing parameters, permitting excellent process stability and universality.
Jinhang Wang   +6 more
wiley   +1 more source

Bioorthogonal Sonodynamic Plug‐and‐Play Targeting Chimeras (SDPTAC) for Precise Targeted Protein Degradation

open access: yesAdvanced Science, EarlyView.
Bioorthogonal SDPTAC harnesses US‐responsive Ce6‐TCO and Tz ligands via IEDDA click chemistry to assemble degraders in situ, generating ROS that selectively eliminate nuclear, cytosolic, and membrane proteins, thereby suppressing deep‐seated tumors in vivo.
Yuhan Bao   +8 more
wiley   +1 more source

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