Results 81 to 90 of about 3,927,016 (290)

Characteristic Gut Microbiota in PCOS-IR Patients and Its Association with Endocrine Features

open access: yesDiabetes, Metabolic Syndrome and Obesity
Wenyi Liang,1,* Yanning Yao,2,* Xinyang Ren,3 Anran Xue,4 Mengcheng Cai,2 Jin Yu,2 Chaoqin Yu,2 Ling Zhou,2 DongXia Zhai2 1School of Pharmacy, Naval Medical University, Shanghai, People’s Republic of China; 2Department of Gynecology of ...
Liang W   +8 more
doaj  

Digoxin Alleviates Osteoarthritis by Inhibiting Macrophage Extracellular Trap Formation via Disruption of the LSP1‐SOD1 Interaction

open access: yesAdvanced Science, EarlyView.
Synovial macrophages in osteoarthritis upregulate LSP1, which directly binds and inhibits SOD1, triggering a redox imbalance that activates both NOX and mitochondrial ROS pathways. This cascade drives the release of macrophage extracellular traps (METs), causing chondrocyte damage and disease progression.
Yankai Pan   +9 more
wiley   +1 more source

Effects and Mechanisms of Wrist-Ankle Acupuncture on Inflammatory Pain in the Rat Gastrocnemius Muscle

open access: yesJournal of Pain Research
Tingting Mai,1,* Mengcheng Cai,1,* Yuhan Tian,1,* Lanyu Jiang,1 Fanfu Fang,1 Wei Gu2 1Department of Rehabilitation Medicine, The First Affiliated Hospital of Naval Medical University, Shanghai, People’s Republic of China; 2School ...
Mai T   +5 more
doaj  

Checkpoint‐Directed Glycoengineering Reprograms the Vascular Lumen for Siglec‐Mediated Immune Regulation

open access: yesAdvanced Science, EarlyView.
Checkpoint‐directed glycoengineering installs sialylated ligands on the donor vascular lumen during ex vivo preservation, creating a localized Siglec‐7/9‐engaging interface. The engineered glycocalyx suppresses immune‐cell activation, complement deposition, and microvascular injury in arterial and kidney allografts while preserving endothelial ...
Md Mohosin Rana   +19 more
wiley   +1 more source

The Emergence of Tropical Medicine in France

open access: yesEmerging Infectious Diseases, 2015
C.J. McKnight
doaj   +1 more source

Case report: tracheobronchial diverticulum, a potential risk for diving?

open access: yesFrontiers in Medicine
Tracheobronchial diverticulum (TBD) is an asymptomatic, benign cystic lesion outside the lumen of the trachea and bronchus. This is the first report case of a SCUBA (self contained underwater breathing apparatus) diver diagnosed with TBD, which is a ...
Long Qing   +6 more
doaj   +1 more source

Foundation Model‐Enabled Pathology‐Informed MRI Model for Preoperative Prediction of Vessels Encapsulating Tumor Clusters in Resectable Hepatocellular Carcinoma: A Multicenter Retrospective Study

open access: yesAdvanced Science, EarlyView.
PIVOT uses pathology‐derived morphologic and vascular representations from postoperative H&E and CD34 whole‐slide images to guide model development, while clinical inference requires only preoperative multiparametric MRI. Across five centers, PIVOT enabled accurate preoperative assessment of vessels encapsulating tumor clusters, stratified patients by ...
Zhehan Shen   +12 more
wiley   +1 more source

Synergistic Immunoregulation: harnessing CircRNAs and PiRNAs to Amplify PD-1/PD-L1 Inhibition Therapy

open access: yesInternational Journal of Nanomedicine
Rui Han,1,2 Xiwu Rao,3 Huiling Zhou,4 Lingeng Lu5– 7 1Department of Chinese Medicine Oncology, The First Affiliated Hospital of Naval Medical University, Shanghai, People’s Republic of China; 2Department of Chinese Medicine, Naval Medical University ...
Han R, Rao X, Zhou H, Lu L
doaj  

The role of NINJ1 in diseases

open access: yesCell Death Discovery
Nerve injury-induced protein 1 (NINJ1) is a multifunctional membrane protein historically studied for its roles in nerve regeneration and cell adhesion.
Shijun Bao   +5 more
doaj   +1 more source

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