Results 61 to 70 of about 3,927,016 (290)

Multifunctional Nanovaccine‐Radiotherapy Synergy Drives Anti‐Tumor Immunity via Multi‐Cascade Cell Death for Pancreatic Cancer Therapy

Advanced Science, EarlyView.
Machine‐learning‐driven transcriptomic analysis identifies FSTL3 as a key tumor‐microenvironment regulator in desmoplastic pancreatic adenocarcinoma. A cRGD‐modified liposome co‐loading gemcitabine and siFSTL3 serves as an irradiation‐triggered in situ nanovaccine. It synergizes with radiotherapy to induce ferroptosis and immunogenic cell death through
Chengyi Huang, Yushu Han, Xiang Liu, Chuanhao Wang, Xiaofei Zhu, Di Chen, Yangyang Gong, Liang Chen, Wenjuan Chen, Zhenyuan Miao, Bufu Tang, Huojun Zhang   +11 more
wiley   +1 more source

Naval Postgraduate Journal [PDF]

, 2002
TransformationNPS Journal is published quarterly by the Naval Postgraduate ...
Naval Postgraduate School (U.S.)
core   +2 more sources

Organic Electrochemical Transistors for Neuromorphic Bioelectronics: Materials and Manufacturing Technologies

Advanced Science, EarlyView.
Organic electrochemical transistors bridge biological ionic signaling and neuromorphic computation through volumetric electrochemical gating. This review connects Organic mixed ionic–electronic conductor materials, device architectures, and manufacturing technologies to show how geometry, ion transport, and fabrication strategies program plasticity ...
Hyunjin Lee, Jihyang Park, Xinyi Wang, Yueqi Deng, Jiashu Ren, Tao Zhou   +5 more
wiley   +1 more source

Nanocarrier-Mediated Immunogenic Cell Death for Melanoma Treatment

International Journal of Nanomedicine, 2023
Jiandong Wang,1– 3,* Jinyuan Ma,1,4,* Zongguang Tai,1,4,* Lisha Li,1,4 Tingrui Zhang,1,4 Tingting Cheng,1– 3 Junxia Yu,1– 3 Quangang Zhu,1,4 Leilei Bao,2 Zhongjian Chen1,4 1Shanghai Skin Disease Hospital, School of Medicine, Tongji University,
Wang J, Ma J, Tai Z, Li L, Zhang T, Cheng T, Yu J, Zhu Q, Bao L, Chen Z   +9 more
doaj  

Naval Warfare Studies Institute Newsletter, 2022-01-13 [PDF]

, 2022
Unnumbered issueHappy New Year! In this issue, we walk you through the emerging technologies branch of the Naval Warfare Studies Institute at Naval Postgraduate School.

core  

Engineered Transformer Base Editor with Enhanced Editing Efficiency

Advanced Science, EarlyView.
A highly efficient transformer base editor system achieves robust genomic editing in a humanized mouse model. This work establishes a versatile and translatable platform, opening new avenues for precision gene therapy. ABSTRACT Canonical cytosine base editors (CBEs) achieve precise C‐to‐T conversions without inducing DNA double‐strand breaks (DSBs ...
Bowen Chen, Letong Liang, Rui Xu, Tianyi Wang, Hongyan Chen, Daru Lu   +5 more
wiley   +1 more source

Serum amino acid alterations in hyperuricemia: potential targets for renal disease prevention

Amino Acids
Observational studies have linked uric acid (UA) levels and kidney disease to amino acid homeostasis, but the causal relationship is unclear. This study aims to determine if elevated UA affects amino acid levels and whether amino acids mediate this ...
Qinglin Sheng, Yuqing Ma, Bingjie Geng, Jiahui Chen, Junfei Cheng, Su Liu, Rui Li, Xiangtong Li, Jing Wang, Hongtao Lu, Fangyuan Gao, Fu Gao   +11 more
doaj   +1 more source

The GPX3‐VCAM1 Axis Gates Pro‐Fibrotic Tubule Cell Fate in Hyperuricemic Nephropathy

Advanced Science, EarlyView.
Hyperuricemia induces NLRP3 inflammasome signaling activation and downregulation of GPX3 in proximal tubular epithelial cells, leading to oxidative stress–driven VCAM1 upregulation, emergence of pro‐fibrotic proximal tubule cells, macrophage recruitment, and renal fibrosis.
Yunfei Qi, Qiang Zhao, Yue Lve, Yaming Yuan, Tingting Zhou, Yue Yuan, Dexi Wu, Yifan Tang, Yan Liu, Zhigang Li, Chunping Jiang, Qiurong Ding   +11 more
wiley   +1 more source

Naval Postgraduate Journal [PDF]

, 2001
The Joint Vision of NPSNPS Journal is published quarterly by the Naval Postgraduate ...
Naval Postgraduate School (U.S.)
core   +1 more source

A Hypoxia-Related miRNA-mRNA Signature for Predicting the Response and Prognosis of Transcatheter Arterial Chemoembolization in Hepatocellular Carcinoma

Journal of Hepatocellular Carcinoma
Shaoqi Zong,1,2,* Guokai Huang,1,3,* Bo Pan,1,* Shasha Zhao,4 Changquan Ling,1,3 Binbin Cheng1,3 1Oncology Department of Traditional Chinese Medicine, The First Affiliated Hospital of Naval Medical University, Shanghai, 200043, People’s ...
Zong S, Huang G, Pan B, Zhao S, Ling C, Cheng B   +5 more
doaj