Results 61 to 70 of about 39,090 (308)

Targeting Golgi–STING Signaling to Reprogram Innate and Adaptive Immunity for the Treatment of Implant‐Associated Infections

Advanced Science, EarlyView.
This study presents an ultrasound‐responsive nanoplatform, CS‐BT@MZ@NEs, with a BaTiO3/Mn‐Zif‐8 core and a chondroitin sulfate coating for Golgi targeting. By leveraging neutrophil hitchhiking, it enables targeted delivery to infection sites. Under ultrasound stimulation, CS‐BT@MZ@NEs generates ROS and modulates Golgi pH to activate cGAS–STING ...
Shicheng Huo, Naifeng Zhu, Zhuocheng Lyu, Yifei Liu, Zhenjiang Xu, Chun Zhou, Yaochao Zhao, Changgui Shi   +7 more
wiley   +1 more source

The relationship between the perceived executive management capabilities of senior Navy Medical Department executives and their reported managerial requirements/ [PDF]

, 1993
The Naval Postgraduate School (NPS) has entered into a partnership with the Bureau of Medicine and Surgery (BUMED) to identify the competencies necessary to effectively function in executive management positions within Navy Medicine and, once the ...
Morrison, John Richard.
core  

Mechanism‐Informed Machine Learning Enables Discovery of Oncolytic Peptides for Cancer Immunotherapy

Advanced Science, EarlyView.
MISPOP integrates ensemble learning with membrane‐active physicochemical priors to identify Dermaseptin‐S9, a natural oncolytic peptide that disrupts tumor membranes, triggers immunogenic cell death, and shows strong antitumor activity. The study illustrates a mechanism‐informed route from peptide sequence data to cancer immunotherapy leads.
Wen Zhang, Shengxin Lu, Guangyong Zheng, Shensuo Li, Hongyu Chen, Mei Hong, Xiangru Zhou, Ruotian Tang, Ye Wu, Weidong Zhang, Dong Lu, Xin Luan   +11 more
wiley   +1 more source

The Efficacy of Chaihu-Guizhi-Ganjiang Decoction on Chronic Non-Atrophic Gastritis with Gallbladder Heat and Spleen Cold Syndrome and Its Metabolomic Analysis: An Observational Controlled Before-After Clinical Trial [Response to Letter]

Drug Design, Development and Therapy
Tao Wen,1,* Xuan Liu,2,* Tao Pang,1,* Mingming Li,1 Guangyang Jiao,3 Xiangcheng Fan,1 Jigui Tang,4 Ci’an Zhang,4 Zhipeng Wang,1 Xiaoqiang Yue,4,* Wansheng Chen,1,3,5 Feng Zhang1,5 1Department of Pharmacy, Changzheng Hospital, Naval ...
Wen T, Liu X, Pang T, Li M, Jiao G, Fan X, Tang J, Zhang C, Wang Z, Yue X, Chen W, Zhang F   +11 more
doaj  

Effective leadership through empowerment: a case study [PDF]

, 1993
In recent year the topic of empowerment has gained much attention among managers. This thesis is a case study analysis of one Naval Hospital Commanding Officer, Captain William R. Rowley, who has a reputation in his community as an innovator and advocate
Newton, Mary Beth.
core  

Making Sweat Measurable: Induction, Sampling, and Refreshment in Wearable Biofluid Sensing

Advanced Science, EarlyView.
Wearable sweat sensing relies not only on chemical detection but also on controlled biofluid management. This Review integrates sweat physiology, induction strategies, and microfluidic sampling architectures, demonstrating how flux, transport, and refreshment shape measurement reliability.
Soyoung Shin, Wei Gao
wiley   +1 more source

Toxic effects of permethrin on HMC3 microglia and its associated mechanism

环境与职业医学
BackgroundPermethrin is a commonly used pyrethroid insecticide and has been found to be potentially neurotoxic. Microglia are innate immune cells in the central nervous system and are involved in the development of a range of neurodegenerative diseases ...
Wanli ZHANG, Wenqi SHAN, Chao CHEN, Haowei DONG, Hao YUAN, Qiuming ZHOU, Feng TAO, Heng PENG, Yajun MA   +8 more
doaj   +1 more source

A Sprayable Nanoplatform Breaks the Vicious Cycle of Diabetic Wounds via Photoactivated Antioxidant and Drug Delivery

Advanced Science, EarlyView.
A sprayable near‐infrared‐activated nanoplatform incorporating MXene, ZnHCF nanozyme, and deferoxamine efficiently breaks the vicious cycle of diabetic wounds. Upon irradiation, interfacial electron transfer and photothermal effects enhance multi‐enzyme activity, enabling explosive ROS elimination, alleviation of hypoxia, and controlled DFO release ...
Jiahao Guo, Yuanyuan Meng, Qixiang Gui, Xi‐Tao Yang, Yong Fan, Xiaodong Zhu   +5 more
wiley   +1 more source

Parliament and the Navy, 1688-1714 [PDF]

, 1968
In these years parliament, particularly the House of Commons, greatly increased its authority. Naval administration and naval operations provided many of the incentives and issues that led parliament to increase its power and status.
Johnston, James Andrew
core  

Layer‐Dependent Phonon Polaritons in hBN Resolved by Photo‐Induced Force Spectroscopy

Advanced Science, EarlyView.
Layer‐dependent phonon polariton resonances in hexagonal boron nitride are systematically investigated using photo‐induced force microscopy. The in‐plane resonance exhibits a blueshift, while the out‐of‐plane resonance shows a redshift with increasing thickness. These results establish layer number as a key parameter for tuning polaritonic responses in
Amin Hajarian, Jiwoo Seo, SungWoo Nam
wiley   +1 more source