Results 31 to 40 of about 2,926,586 (240)
Molecular Oncology, EarlyView.Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Molecular Oncology, EarlyView.Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source
Heavy baryon decay widths in the large $$N_c$$ Nc limit in chiral theory
European Physical Journal C: Particles and Fields, 2018 We propose large $$N_c$$ Nc generalizations for the “diquark” representations of $$\hbox {SU}(3)_\mathrm{flav}$$ SU(3)flav relevant for positive parity heavy baryons, including putative exotic states.
Michal Praszalowicz
doaj +1 more source
Molecular Oncology, EarlyView.Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani +9 more
wiley +1 more source
Kontrolle von NC-Programmen durch Simulationssysteme
, 2022 Mit einem dynamischen Simulationssystem wird am Bildschirm aus dem Rohteil das Fertigteil produziert. Die Verfahrbewegung sowie der Eingriff des Werkzeuges am Werkstück können dabei kontrolliert und auf Ablauffehler überprüft werden.
Potthast, A.
core +1 more source
IEEE Access, 2019 Recently, various process reuse technologies have come to be widely used in manufacturing. The existing methods mainly focus on searching and reusing similar NC processes.
Bo Huang +5 more
doaj +1 more source
Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells
FEBS Open Bio, EarlyView.Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim +4 more
wiley +1 more source
Delivery of DNA‐encoded vaccines and proteins in mice using cutaneous suction‐mediated transfection
FEBS Open Bio, EarlyView.Cutaneous suction‐mediated transfection in mice for delivery of DNA‐encoded vaccines and proteins. A critical limitation of DNA vaccines and other therapeutics is transfection in vivo to produce the encoded antigens or therapeutic proteins. Cutaneous suction‐based methods have demonstrated effectiveness in many animal models and have been successfully ...
Emran O. Lallow +12 more
wiley +1 more source
Determinação automatica de condições de usinagem na programação APT de maquinas NC [PDF]
, 1988 Dissertação (mestrado) - Universidade Federal de Santa Catarina. Centro TecnologicoNeste trabalho é apresentado um sistema de otimização de condições de usinagem no fresamento para auxiliar a programação APT (Automatically Programmed Tool) de máquinas de
Girondi, Amyr Elmo de Castro
core
Heterotropic regulation and negative homotropic cooperativity
FEBS Open Bio, EarlyView.We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea +5 more
wiley +1 more source