Results 41 to 50 of about 4,277,308 (278)
Annals of Pure and Applied Logic, 1991 The characterization of classes of polynomially bounded functions by means of bounded arithmetic is the central theme of this paper. The three concepts: 1) Boolean circuit definable, 2) (mathematically) recursion definable and 3) representable in bounded arithmetic are analyzed and compared.
openaire +2 more sources
A Basic Result on the Superposition of Arrival Processes in Deterministic Networks
, 2018 Time-Sensitive Networking (TSN) and Deterministic Networking (DetNet) are emerging standards to enable deterministic, delay-critical communication in such networks. This naturally (re-)calls attention to the network calculus theory (NC), since a rich set
Jiang, Yuming
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Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Health education as education of the oppressed
Curationis, 1999 Paolo Freire’s theory of critical thinking shows remarkable similarities to the principles supported by health education. In his capacity as Brazilian educationalist, Freire emphasized man’s active participation in his own development.
NC van Wyk
doaj +1 more source
Three-nucleon forces in the 1/Nc expansion [PDF]
, 2013 The operator structures that can contribute to three-nucleon forces are classified in the 1/Nc expansion. At leading order in 1/Nc a spin-flavor independent term is present, as are the spin-flavor structures associated with the Fujita-Miyazawa three ...
Phillips, Daniel R., Schat, Carlos
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Molecular Oncology, EarlyView.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
Crossed Module Bundle Gerbes; Classification, String Group and Differential Geometry
, 2005 We discuss nonabelian bundle gerbes and their differential geometry using simplicial methods. Associated to any crossed module there is a simplicial group NC, the nerve of the 1-category defined by the crossed module and its geometric realization |NC ...
Aschieri P. +7 more
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COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata +10 more
wiley +1 more source