Results 61 to 70 of about 4,277,308 (278)
Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system
FEBS Open Bio, EarlyView.An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková +3 more
wiley +1 more source
Harnessing ferroelectric domains for negative capacitance
, 2018 The pressing quest for overcoming Boltzmann tyranny in low-power nanoscale electronics revived the thoughts of engineers of early 1930-s on the possibility of negative circuit constants.
Luk'yanchuk, I. +4 more
core +4 more sources
Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs
FEBS Open Bio, EarlyView.Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner +7 more
wiley +1 more source
On finite-density QCD at large Nc
, 1999 Deryagin, Grigoriev, and Rubakov (DGR) have shown that in finite-density QCD at infinite Nc the Fermi surface is unstable with respect to the formation of chiral waves with wavenumber twice the Fermi momentum, while the BCS instability is suppressed.
't Hooft +13 more
core +3 more sources
FEBS Open Bio, EarlyView.Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source
Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer
Aging and Cancer, EarlyView.Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss +12 more
wiley +1 more source
Modeling Network Coded TCP Throughput: A Simple Model and its Validation
, 2010 We analyze the performance of TCP and TCP with network coding (TCP/NC) in lossy wireless networks. We build upon the simple framework introduced by Padhye et al. and characterize the throughput behavior of classical TCP as well as TCP/NC as a function of
Barros, Joao, Kim, MinJi, Medard, Muriel
core +3 more sources
Discovery and Targeted Proteomic Studies Reveal Striatal Markers Validated for Huntington's Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Clinical trials for Huntington's disease (HD) enrolling persons before clinical motor diagnosis (CMD) lack validated biomarkers. This study aimed to conduct an unbiased discovery analysis and a targeted examination of proteomic biomarkers scrutinized by clinical validation. Methods Cerebrospinal fluid was obtained from PREDICT‐HD and
Daniel Chelsky +8 more
wiley +1 more source
Recent Developments In Bronchial Thermoplasty For Severe Asthma
Journal of Asthma and Allergy, 2019 Neil C Thomson Institute of Infection, Immunity & Inflammation, University of Glasgow, Glasgow, UKCorrespondence: Neil C ThomsonInstitute of Infection, Immunity & Inflammation, University of Glasgow, Glasgow G12 OYN, UKTel +44-141-211-1673Email ...
Thomson NC
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A new CNC programming method using STEP-NC protocol [PDF]
FME Transactions, 2017 A new programming method of CNC Machine tools, which is developing as an alternative to G code, is AP238 protocol or STEP-NC, according to ISO 10303 standard.
Živanović Saša T., Vasilić Goran V.
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